Evidence map›Paper›PMID 34043473›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021

Arterial load and right ventricular-vascular coupling in pulmonary hypertension.

Hannah Oakland, Phillip Joseph, Robert Naeije, Ahmed Elassal, Marjorie Cullinan, Paul M Heerdt, Inderjit Singh

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Wave intensity analysis with exercise identifies impairments in pulmonary hypertension.American journal of physiology. Heart and circulatory physiology · 2025
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  7. Review
  8. Article
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  16. Observational
  17. Reply to Grignola and Trujillo.Journal of applied physiology (Bethesda, Md. : 1985) · 2022
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hannah OaklandDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale New Haven Hospital and Yale School of Medicine, New Haven, Connecticut.
Phillip JosephDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale New Haven Hospital and Yale School of Medicine, New Haven, Connecticut.
Robert NaeijeSchool of Medicine, Free University of Brussels, Brussels, Belgium.
Ahmed ElassalDivision of Applied Hemodynamics, Department of Anesthesiology, Yale New Haven Hospital and Yale School of Medicine, New Haven, Connecticut.ORCID 0000-0002-9569-7765
Marjorie CullinanDepartment of Respiratory Care, Yale New Haven Hospital, New Haven, Connecticut.
Paul M HeerdtDivision of Applied Hemodynamics, Department of Anesthesiology, Yale New Haven Hospital and Yale School of Medicine, New Haven, Connecticut.
Inderjit SinghDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale New Haven Hospital and Yale School of Medicine, New Haven, Connecticut.
Yale New Haven Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Training Translational Lung Biology and PathobiologyT32HL007778 · NHLBI · YALE UNIVERSITY · PI Erica L Herzog, NAFTALI KAMINSKI · 1994 to 2026
$14.4M
Research Training in AnesthesiaT32GM086287 · NIGMS · YALE UNIVERSITY · PI ROBERT SCHONBERGER · 2009 to 2026
$3.7M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS T32 HL007778NIGMS NIH HHS T32 GM086287
6 · The paper itself

Abstract

Right ventricular (RV) functional adaptation to afterload determines outcome in pulmonary hypertension (PH). RV afterload is determined by the dynamic interaction between pulmonary vascular resistance (PVR), characteristic impedance (

Indexed as

Heart FailureHypertension, PulmonaryVentricular Dysfunction, RightAnimalsHeart VentriclesHumansPulmonary ArteryStroke VolumeVentricular Function, Rightheart failure with preserved ejection fractionpulmonary arterial hypertensionright ventricle-pulmonary artery couplingvascular impedancewave reflection

Identifiers

PMID34043473
PMCPMC8325619
OpenAlexW3165812316

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.