Evidence map›Paper›PMID 34046069›Full record

ReviewStem cells international2021

Key Markers and Epigenetic Modifications of Dental-Derived Mesenchymal Stromal Cells.

Jingqiu Chen, Xiaodan Zheng, Nanquan Rao, Yao Huang, Juan Liu, Yanhong Li, Jun Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Stem cells international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Identification of GLDNInternational journal of oral science · 2026
    Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jingqiu ChenYunnan Provincial Key Laboratory of Stomatology, The Affiliated Stomatology Hospital of Kunming Medical University, Kunming, Yunnan, China.
Xiaodan ZhengYunnan Provincial Key Laboratory of Stomatology, The Affiliated Stomatology Hospital of Kunming Medical University, Kunming, Yunnan, China.
Nanquan RaoYunnan Provincial Key Laboratory of Stomatology, The Affiliated Stomatology Hospital of Kunming Medical University, Kunming, Yunnan, China.
Yao HuangYunnan Provincial Key Laboratory of Stomatology, The Affiliated Stomatology Hospital of Kunming Medical University, Kunming, Yunnan, China.
Juan LiuYunnan Provincial Key Laboratory of Stomatology, The Affiliated Stomatology Hospital of Kunming Medical University, Kunming, Yunnan, China.
Yanhong LiYunnan Provincial Key Laboratory of Stomatology, The Affiliated Stomatology Hospital of Kunming Medical University, Kunming, Yunnan, China.
Jun ZhangYunnan Provincial Key Laboratory of Stomatology, The Affiliated Stomatology Hospital of Kunming Medical University, Kunming, Yunnan, China.ORCID https://orcid.org/0000-0002-9170-2555
Kunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a novel research hotspot in tissue regeneration, dental-derived mesenchymal stromal cells (MSCs) are famous for their accessibility, multipotent differentiation ability, and high proliferation. However, cellular heterogeneity is a major obstacle to the clinical application of dental-derived MSCs. Here, we reviewed the heterogeneity of dental-derived MSCs firstly and then discussed the key markers and epigenetic modifications related to the proliferation, differentiation, immunomodulation, and aging of dental-derived MSCs. These messages help to control the composition and function of dental-derived MSCs and thus accelerate the translation of cell therapy into clinical practice.

Identifiers

PMID34046069
PMCPMC8128613
OpenAlexW3162484576

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.