Evidence map›Paper›PMID 34046505›Full record

ReviewJournal of diabetes research2021

Pain Management in People with Diabetes-Related Chronic Limb-Threatening Ischemia.

Xiaoyan Jiang, Yi Yuan, Yu Ma, Miao Zhong, Chenzhen Du, Johnson Boey, David G Armstrong, Wuquan Deng, Xiaodong Duan

Open access · goldAbstract readReview
In one paragraph

Review in Journal of diabetes research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Guideline
  2. World journal of diabetes · 2025
    Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Xiaoyan JiangDepartment of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, China.ORCID https://orcid.org/0000-0002-1968-6810
Yi YuanDepartment of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, China.ORCID https://orcid.org/0000-0002-5603-4723
Yu MaDepartment of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, China.
Miao ZhongDepartment of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, China.ORCID https://orcid.org/0000-0002-7815-7046
Chenzhen DuDepartment of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, China.ORCID https://orcid.org/0000-0003-1796-6592
Johnson BoeyDepartment of Podiatry, National University of Hospital Singapore, Singapore 169608.ORCID https://orcid.org/0000-0001-9466-7241
David G ArmstrongKeck School of Medicine of University of Southern California, Los Angeles, CA 90033, USA.ORCID https://orcid.org/0000-0003-1887-9175
Wuquan DengDepartment of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, China.ORCID https://orcid.org/0000-0002-9883-5051
Xiaodong DuanDepartment of Rehabilitation, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China.ORCID https://orcid.org/0000-0002-6295-5051
Chongqing University · CNAffiliated Hospital of Southwest Medical University · CNNational University Hospital · SGUniversity of Southern California · US

Funding

Improving the science of adherence reinforcement and safe mobility in people with diabetic foot ulcers using smart offloadingR01DK124789 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ARMSTRONG, DAVID GEORGE, NAJAFI, BIJAN · 2021 to 2025
$2.0M
Infrared Eyes(iREyes)R44DK102244 · NIDDK · EDEN MEDICAL, INC. · PI ARMSTRONG, DAVID GEORGE, SCHOESS, JEFFREY NORMAN · 2018 to 2020
$1.7M
NIDDK NIH HHS R01 DK124789NIDDK NIH HHS R44 DK102244
6 · The paper itself

Abstract

Management of neuropathic pain in people with diabetes has been widely investigated. However, little attention was paid to address ischemic-related pain in patients with diabetes mellitus who suffered from chronic limb-threatening ischemia (CLTI), the end stage of lower extremity arterial disease (LEAD). Pain management has a tremendous influence on patients' quality of life and prognosis. Poor management of this type of pain owing to the lack of full understanding undermines patients' physical and mental quality of life, which often results in a grim prognosis, such as depression, myocardial infarction, lower limb amputation, and even mortality. In the present article, we review the current strategy in the pain management of diabetes-related CLTI. The endovascular therapy, pharmacological therapies, and other optional methods could be selected following comprehensive assessments to mitigate ischemic-related pain, in line with our current clinical practice. It is very important for clinicians and patients to strengthen the understanding and build intervention strategy in ischemic pain management and possible adverse consequence.

Indexed as

Pain ManagementChronic DiseaseDiabetes MellitusHumansIschemiaPeripheral Arterial DiseaseQuality of LifeRisk FactorsTreatment Outcome

Identifiers

PMID34046505
PMCPMC8128546
OpenAlexW3162192296

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.