Evidence map›Paper›PMID 34046795›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2021

Remote smartphone gait monitoring and fall prediction in Parkinson's disease during the COVID-19 lockdown.

Massimo Marano, Francesco Motolese, Mariagrazia Rossi, Alessandro Magliozzi, Ziv Yekutieli, Vincenzo Di Lazzaro

Abstract read
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Instrumental assessment of Sit-to-Stand in Parkinson's disease: a scoping review.Journal of neuroengineering and rehabilitation · 2026
    Article
  4. Article
  5. Article
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  7. Fear of falling impairs spatiotemporal gait parameters, mobility, and quality of life in Parkinson's disease: a cross-sectional study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  8. Article
  9. Article
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  11. Transcutaneous Auricular Vagus Stimulation Improves Gait and Reaction Time in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Massimo MaranoNeurology, Neurophysiology and Neurobiology Unit, Department of Medicine, Università Campus Bio-Medico Di Roma, Viale Alvaro del Portillo, 21, 00128, Rome, Italy. m.marano@unicampus.it.ORCID http://orcid.org/0000-0001-9885-3666
Francesco MotoleseNeurology, Neurophysiology and Neurobiology Unit, Department of Medicine, Università Campus Bio-Medico Di Roma, Viale Alvaro del Portillo, 21, 00128, Rome, Italy.
Mariagrazia RossiNeurology, Neurophysiology and Neurobiology Unit, Department of Medicine, Università Campus Bio-Medico Di Roma, Viale Alvaro del Portillo, 21, 00128, Rome, Italy.
Alessandro MagliozziNeurology, Neurophysiology and Neurobiology Unit, Department of Medicine, Università Campus Bio-Medico Di Roma, Viale Alvaro del Portillo, 21, 00128, Rome, Italy.
Ziv YekutieliMontfort Brain Monitor, Binyamina, Israel.
Vincenzo Di LazzaroNeurology, Neurophysiology and Neurobiology Unit, Department of Medicine, Università Campus Bio-Medico Di Roma, Viale Alvaro del Portillo, 21, 00128, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFalls could be serious events in Parkinson's disease (PD). Patient remote monitoring strategies are on the raise and may be an additional aid in identifying patients who are at risk of falling. The aim of the study was to evaluate if balance and timed-up-and-go data obtained by a smartphone application during COVID-19 lockdown were able to predict falls in PD patients.

methodsA cohort of PD patients were monitored for 4 weeks during the COVID-19 lockdown with an application measuring static balance and timed-up-and-go test. The main outcome was the occurrence of falls (UPDRS-II item 13) during the observation period.

resultsThirty-three patients completed the study, and 4 (12%) reported falls in the observation period. The rate of falls was reduced with respect to patient previous falls history (24%). The stand-up time and the mediolateral sway, acquired through the application, differed between "fallers" and "non-fallers" and related to the occurrence of new falls (OR 1.7 and 1.6 respectively, p < 0.05), together with previous falling (OR 7.5, p < 0.01). In a multivariate model, the stand-up time and the history of falling independently related to the outcome (p < 0.01).

conclusionsOur study provides new data on falls in Parkinson's disease during the lockdown. The reduction of falling events and the relationship with the stand-up time might suggest that a different quality of falls occurs when patient is forced to stay home - hence, clinicians should point their attention also on monitoring patients' sit-to-stand body transition other than more acknowledged features based on step quality.

Indexed as

COVID-19Parkinson DiseaseCommunicable Disease ControlGaitGait AnalysisHumansPostural BalanceSARS-CoV-2SmartphoneTime and Motion StudiesFallsGaitParkinson’s diseaseRemote patient monitoringSensorsTimed-up-and-go test

Identifiers

PMID34046795
PMCPMC8159018

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.