Evidence map›Paper›PMID 34048833›Full record

ReviewInternational journal of biological macromolecules2021

Classification, structure and mechanism of antiviral polysaccharides derived from edible and medicinal fungus.

Yuxi Guo, Xuefeng Chen, Pin Gong

Open access · greenAbstract readReview
In one paragraph

Review in International journal of biological macromolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 84 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Identification and Nutrient Composition of a WildFoods (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Review
  11. Unveiling the Texture Secrets ofFoods (Basel, Switzerland) · 2025
    Article
  12. Research on the Action and Mechanism of Pharmacological Components ofInternational journal of molecular sciences · 2024
    Review
  13. Article
  14. Article
  15. Nutritional Assessment ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  16. Protective Effect ofMolecules (Basel, Switzerland) · 2023
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yuxi GuoSchool of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an 710021, China.
Xuefeng ChenSchool of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an 710021, China; Shaanxi Research Institute of Agricultural Product Processing Technology, Xi'an 710021, China.
Pin GongSchool of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an 710021, China. Electronic address: gongpin@sust.edu.cn.
Shaanxi University of Science and Technology · CNHunan Agricultural Products (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The deficiency of chemical-synthesized antiviral drugs when applied in clinical therapy, such as drug resistance, and the lack of effective antiviral drugs to treat some newly emerging virus infections, such as COVID-19, promote the demand of novelty and safety anti-virus drug candidate from natural functional ingredient. Numerous studies have shown that some polysaccharides sourcing from edible and medicinal fungus (EMFs) exert direct or indirect anti-viral capacities. However, the internal connection of fungus type, polysaccharides structural characteristics, action mechanism was still unclear. Herein, our review focus on the two aspects, on the one hand, we discussed the type of anti-viral EMFs and the structural characteristics of polysaccharides to clarify the structure-activity relationship, on the other hand, the directly or indirectly antiviral mechanism of EMFs polysaccharides, including virus function suppression, immune-modulatory activity, anti-inflammatory activity, regulation of population balance of gut microbiota have been concluded to provide a comprehensive theory basis for better clinical utilization of EMFs polysaccharides as anti-viral agents.

Indexed as

Anti-Inflammatory AgentsAntiviral AgentsCOVID-19 Drug TreatmentFungal PolysaccharidesImmunologic FactorsAgaricalesCOVID-19Gastrointestinal MicrobiomeHumansSARS-CoV-2Anti-Inflammatory AgentsAntiviral AgentsFungal PolysaccharidesImmunologic FactorsAntiviral activityEdible and medicinal fungusPolysaccharides

Identifiers

PMID34048833
PMCPMC8144117
OpenAlexW3164687506

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.