Evidence mapPaperPMID 34055047Full record

ArticleJournal of functional foods2021

Virgin coconut oil is effective in lowering C-reactive protein levels among suspect and probable cases of COVID-19.

Imelda Angeles-Agdeppa, Jacus S Nacis, Mario V Capanzana, Fabian M Dayrit, Keith V Tanda

Abstract read
In one paragraph

Article in Journal of functional foods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Imelda Angeles-AgdeppaDepartment of Science and Technology, Food and Nutrition Research Institute, Taguig City 1631, Philippines.
Jacus S NacisDepartment of Science and Technology, Food and Nutrition Research Institute, Taguig City 1631, Philippines.
Mario V CapanzanaDepartment of Science and Technology, Food and Nutrition Research Institute, Taguig City 1631, Philippines.
Fabian M DayritDepartment of Chemistry, Ateneo de Manila University, Quezon City 1108, Philippines.
Keith V TandaDepartment of Science and Technology, Food and Nutrition Research Institute, Taguig City 1631, Philippines.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the complex pathogenesis of COVID-19 continues to evolve. With observation and quarantine as the prevailing standard of care, this study evaluated the effects of virgin coconut oil (VCO) in the biochemical markers of suspect and probable cases of COVID-19. A 28-day randomized, double-blind, controlled intervention was conducted among 63 adults in two isolation facilities in Santa Rosa City, Laguna, Philippines. The participants were randomly assigned to receive either a standardized meal (control) or a standardized meal mixed with a predefined dosage of VCO. Changes in clinical markers were measured at three time points (day 0, 14, and 28), with daily monitoring of COVID-19 symptoms. Participants in the intervention group showed a significant decline in the C-reactive protein level, with the mean CRP level normalized to ≤ 5 mg/dL on the 14th day of the intervention. As an adjunct therapy, meals mixed with VCO is effective fostering faster recovery from COVID-19.

Indexed as

COVID-19C-reactive proteinLauric acidMonolaurinVirgin coconut oil

Identifiers

PMID34055047
PMCPMC8142857

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.