Evidence map›Paper›PMID 34061973›Full record

ArticleCancer2021

Material, behavioral, and psychological financial hardship among survivors of childhood cancer in the Childhood Cancer Survivor Study.

Douglas Fair, Elyse R Park, Ryan D Nipp, Julia Rabin, Kelly Hyland, Karen Kuhlthau, Giselle K Perez, Paul C Nathan, Gregory T Armstrong, Kevin C Oeffinger and 3 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05527392 (Assessing the Effect of Virtual Navigation Interventions to Improve Health Insurance Literacy and Decrease Financial Burden), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05527392 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Assessing the Effect of Virtual Navigation Interventions to Improve Health Insurance Literacy and Decrease Financial Burden: A Childhood Cancer Survivor Study Randomized Trial (HINTII)

TypeinterventionalSponsorMassachusetts General HospitalRan2023 to 2027Enrolled529ConditionsChildhood Cancer SurvivorsArmsHealth Insurance Navigation Tools Program
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Sources of informal financial support among adolescent and young adult cancer survivors: a mixed methods analysis from the HIAYA CHAT study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Trial
  6. Review
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Development of a Health Insurance Navigation Program for Long-Term Childhood Cancer Survivors.Health education & behavior : the official publication of the Society for Public Health Education · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Experiences of adolescent and young adult cancer survivors during the COVID-19 pandemic.Journal of cancer survivorship : research and practice · 2023
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Douglas FairUniversity of Utah, Salt Lake City, Utah.ORCID 0000-0001-9742-4640
Elyse R ParkMassachusetts General Hospital, Boston, Massachusetts.ORCID 0000-0002-6319-264X
Ryan D NippMassachusetts General Hospital, Boston, Massachusetts.ORCID 0000-0002-4577-3248
Julia RabinMassachusetts General Hospital, Boston, Massachusetts.
Kelly HylandMassachusetts General Hospital, Boston, Massachusetts.
Karen KuhlthauMassachusetts General Hospital, Boston, Massachusetts.
Giselle K PerezMassachusetts General Hospital, Boston, Massachusetts.
Paul C NathanThe Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-0334-0871
Gregory T ArmstrongSt. Jude Children's Research Hospital, Memphis, Tennessee.
Kevin C OeffingerDuke Cancer Institute, Duke University, Durham, North Carolina.
Leslie L RobisonSt. Jude Children's Research Hospital, Memphis, Tennessee.
Wendy LeisenringFred Hutchinson Cancer Research Center, Seattle, Washington.
Anne C KirchhoffUniversity of Utah, Salt Lake City, Utah.
Massachusetts General Hospital · USSt. Jude Children's Research Hospital · USUniversity of Utah · USDuke Medical Center · USFred Hutch Cancer Center · USUniversity of Toronto · CA

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Shondra Michelle Miller · 1985 to 2026
$166.9M
Mach-LETSGO: Machine-LEarning of Treatment, Survey, and Genetics towards Obtaining Correct Classification of Chronic Conditions in Adult Survivors in the Childhood Cancer Survivor Study - CCSS SupplU24CA055727 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Gregory Armstrong · 1999 to 2026
$96.7M
Examining Delivery of Integrated Tobacco Treatment in Cancer CareK24CA197382 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI PARK, ELYSE R. · 2015 to 2019
$841k
American Lebanese-Syrian Associated Charities (ALSAC)Cancer Center Support (CORE) GrantNCI NIH HHS K24 CA197382NCI NIH HHS P30 CA021765NCI NIH HHS U24 CA055727
6 · The paper itself

Abstract

backgroundMedical financial burden includes material, behavioral, and psychological hardship and has been underinvestigated among adult survivors of childhood cancer.

methodsA survey from 698 survivors and 210 siblings from the Childhood Cancer Survivor Study was analyzed. The intensity of financial hardship was estimated across 3 domains: 1) material, including conditions that arise from medical expenses; 2) behavioral, including coping behaviors to manage medical expenses; and 3) psychological hardship resulting from worries about medical expenses and insurance, as measured by the number of instances of each type of financial hardship (0, 1-2, and ≥3 instances). Multivariable logistic regressions were conducted to examine the clinical and sociodemographic predictors of experiencing financial hardship (0-2 vs ≥3 instances).

resultsThe intensity of financial hardship did not significantly differ between survivors and siblings. Survivors reported more instances of material hardship than siblings (1-2 instances: 27.2% of survivors vs 22.6% of siblings; ≥3 instances: 15.9% of survivors vs 11.4% siblings; overall P = .03). In multivariable regressions, insurance was protective against all domains of financial hardship (behavioral odds ratio [OR], 0.12; 95% confidence interval [CI], 0.06-0.22; material OR, 0.37; 95% CI, 0.19-0.71; psychological OR, 0.10; 95% CI, 0.05-0.21). Survivors who were older at diagnosis, female, and with chronic health conditions generally had higher levels of hardship. Brain radiation and alkylating agents were associated with higher levels of hardship.

conclusionsMaterial, behavioral, and psychological financial burden among survivors of childhood cancer is common.

Indexed as

Cancer SurvivorsNeoplasmsAdultChildCost of IllnessFemaleFinancial StressHealth ExpendituresHumansSurvivorscancer survivorsfinancial hardshipsurvivors of childhood cancer

Identifiers

PMID34061973
PMCPMC8489494
OpenAlexW3164737310

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.