Evidence map›Paper›PMID 34062261›Full record

Trial reportExperimental gerontology2021

The influence of a 16-week exercise program, APOE status, and age on executive function task performance: A randomized trial.

R Martin-Willett, B Morris, R Wilcox, G Giordano, J Andrews-Hanna, M Banich, A B Bryan

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Experimental gerontology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

R Martin-WillettThe University of Colorado Boulder, Boulder, CO, United States of America. Electronic address: renee.martinwillett@colorado.edu.
B MorrisThe University of Colorado Boulder, Boulder, CO, United States of America.
R WilcoxThe University of Illinois, Champaign, IL, United States of America.
G GiordanoThe University of Colorado Boulder, Boulder, CO, United States of America.
J Andrews-HannaThe University of Arizona, Tucson, AZ, United States of America.
M BanichThe University of Colorado Boulder, Boulder, CO, United States of America.
A B BryanThe University of Colorado Boulder, Boulder, CO, United States of America.

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
Enhancing function in later life: Exercise and functional network connectivityR01AG043452 · NIA · UNIVERSITY OF COLORADO · PI BRYAN, ANGELA · 2014 to 2018
$2.9M
NCRR NIH HHS UL1 RR025780NIA NIH HHS R01 AG043452
6 · The paper itself

Abstract

Previous research has shown beneficial cognitive changes following exercise training in older adults. However, the work on the potential moderating effects of Apoliprotein E (APOE) ε4 carrier status has been mixed, and the role of exercise intensity remains largely unexplored. The present study sought to examine the influence of APOE ε4 status and exercise intensity on measures of cognitive performance in a group of older adults. Cross-sectional comparisons between a group of younger inactive adults (n = 44, age = 28.86 ± 0.473 SD, 60.5% female) and a group of older inactive adults (n = 142, age = 67.8 ± 5.4, 62.7% female) were made on baseline measurements of APOE ε4 status, VO

Indexed as

Apolipoprotein E4Executive FunctionAgedCognitionCross-Sectional StudiesExerciseExercise TherapyFemaleHumansMaleApolipoprotein E4APOECognitionExecutive functionExerciseOlder adults

Identifiers

PMID34062261
PMCPMC8319074

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.