Serum Periostin as a Potential Biomarker in Pediatric Patients with Primary Hypertension.

Michał Szyszka, Piotr Skrzypczyk, Anna Stelmaszczyk-Emmel, Małgorzata Pańczyk-Tomaszewska

Open access · goldAbstract read

In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.3field-weighted citation impact, top 40% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michał SzyszkaDepartment of Pediatrics and Nephrology, Doctoral School, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-7336-7327

Piotr SkrzypczykDepartment of Pediatrics and Nephrology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-1959-8255

Anna Stelmaszczyk-EmmelDepartment of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0003-3667-1220

Małgorzata Pańczyk-TomaszewskaDepartment of Pediatrics and Nephrology, Medical University of Warsaw, 02-091 Warsaw, Poland.

Medical University of Warsaw · PL

Funding

Statutory funds of the Department of Pediatrics and Nephrology, Medical University of Warsaw no grant number

6 · The paper itself

Abstract

Experimental studies suggest that periostin is involved in tissue repair and remodeling. The study aimed to evaluate serum periostin concentration as potential biomarker in pediatric patients with primary hypertension (PH). We measured serum periostin, blood pressure, arterial damage, biochemical, and clinical data in 50 children with PH and 20 age-matched healthy controls. In univariate analysis, children with PH had significantly lower serum periostin compared to healthy peers (35.42 ± 10.43 vs. 42.16 ± 12.82 [ng/mL],

Indexed as

adolescentsarterial damageblood pressurechildrenperiostinprimary hypertension

Identifiers

PMID34063373

DOI10.3390/jcm10102138

PMCPMC8156565

OpenAlexW3163285601

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.