Evidence map›Paper›PMID 34064308›Full record

ArticleNutrients2021

Leptin Receptors Are Not Required for Roux-en-Y Gastric Bypass Surgery to Normalize Energy and Glucose Homeostasis in Rats.

Mohammed K Hankir, Laura Rotzinger, Arno Nordbeck, Caroline Corteville, Ulrich Dischinger, Juna-Lisa Knop, Annett Hoffmann, Christoph Otto, Florian Seyfried

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mohammed K HankirDepartment of General, Visceral, Vascular and Pediatric Surgery, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Laura RotzingerDepartment of General, Visceral, Vascular and Pediatric Surgery, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Arno NordbeckDepartment of General, Visceral, Vascular and Pediatric Surgery, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Caroline CortevilleDepartment of General, Visceral, Vascular and Pediatric Surgery, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Ulrich DischingerDepartment of Endocrinology, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Juna-Lisa KnopDepartment of General, Visceral, Vascular and Pediatric Surgery, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Annett HoffmannDepartment of General, Visceral, Vascular and Pediatric Surgery, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Christoph OttoDepartment of General, Visceral, Vascular and Pediatric Surgery, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.
Florian SeyfriedDepartment of General, Visceral, Vascular and Pediatric Surgery, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.ORCID 0000-0002-5915-8692
Universitätsklinikum Würzburg · DE

Funding

Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg Z-3/44
6 · The paper itself

Abstract

Sensitization to the adipokine leptin is a promising therapeutic strategy against obesity and its comorbidities and has been proposed to contribute to the lasting metabolic benefits of Roux-en-Y gastric bypass (RYGB) surgery. We formally tested this idea using Zucker fatty

Indexed as

AnimalsBlood GlucoseDisease Models, AnimalEnergy MetabolismFatty LiverGastric BypassGlucagon-Like Peptide 1Glucose Tolerance TestHomeostasisInsulinObesityPostoperative PeriodRatsRats, WistarRats, ZuckerReceptors, LeptinBlood GlucoseGlucagon-Like Peptide 1InsulinReceptors, Leptinenergy homeostasisfatty liverglucose homeostasisleptin systemRoux-en-Y gastric bypass surgeryZucker fatty fa/fa rats

Identifiers

PMID34064308
PMCPMC8147759
OpenAlexW3157393588

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.