Evidence mapPaperPMID 34064348Full record

Trial reportBiomolecules2021

Trace Element and Mineral Levels in Serum, Hair, and Urine of Obese Women in Relation to Body Composition, Blood Pressure, Lipid Profile, and Insulin Resistance.

Alexey A Tinkov, Paweł Bogdański, Damian Skrypnik, Katarzyna Skrypnik, Anatoly V Skalny, Jan Aaseth, Margarita G Skalnaya, Joanna Suliburska

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  14. Correlates of whole blood metal concentrations among reproductive-aged Black women.Journal of exposure science & environmental epidemiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Alexey A TinkovLaboratory of Ecobiomonitoring and Quality Control, Yaroslavl State University, Sovetskaya St., 14, 150000 Yaroslavl, Russia.
Paweł BogdańskiDepartment of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznań University of Medical Sciences, Szamarzewskiego St. 84, 60-569 Poznań, Poland.ORCID 0000-0002-0563-1624
Damian SkrypnikDepartment of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznań University of Medical Sciences, Szamarzewskiego St. 84, 60-569 Poznań, Poland.ORCID 0000-0001-5643-6899
Katarzyna SkrypnikDepartment of Human Nutrition and Dietetics, Poznan University of Life Science, ul. Wojska Polskiego 31, 60-624 Poznan, Poland.
Anatoly V SkalnyLaboratory of Ecobiomonitoring and Quality Control, Yaroslavl State University, Sovetskaya St., 14, 150000 Yaroslavl, Russia.
Jan AasethDepartment of Research, Innlandet Hospital Trust, 2380 Brumunddal, Norway.ORCID 0000-0002-7518-5703
Margarita G SkalnayaLaboratory of Ecobiomonitoring and Quality Control, Yaroslavl State University, Sovetskaya St., 14, 150000 Yaroslavl, Russia.
Joanna SuliburskaDepartment of Human Nutrition and Dietetics, Poznan University of Life Science, ul. Wojska Polskiego 31, 60-624 Poznan, Poland.
Yaroslavl State University · RUPoznan University of Medical Sciences · PLUniversity of Life Sciences in Poznań · PLInnlandet Hospital Trust · NO

Funding

Russian Ministry of Science and Higher Education 0856-2020-0008
6 · The paper itself

Abstract

The objective of this study was to evaluate serum, hair, and urinary trace element and mineral content in normal-weight and obese women in relation to metabolic risk factors. A total of 80 women aged 30-70 y.o. were enrolled in the obese group (n = 40) and normal-weight group (n = 40). Serum, hair, and urinary trace element and mineral levels were assessed using inductively coupled plasma spectrometry. Body fat percentage was evaluated using bioimpedance. Obese subjects were characterized by significantly higher body fat percentage, blood pressure, serum triglyceride concentration, and insulin resistance. Serum Ca, Fe, Mg, Se, V, Zn levels, hair Fe, Mg, V content, and urinary Se and V concentrations were found to be lower in obese subjects as compared to lean controls. In turn, serum Cu and urinary Fe levels in obese women were characterized by a significant increase. In multiple regression models serum Cu, Se, and Zn levels were significantly associated with BMI even after adjustment for blood biochemistry, body composition, and blood pressure. Serum trace element and mineral levels also significantly contributed to group discrimination. These findings allow to propose that obesity-associated disturbances in trace element and mineral status may at least partially contribute to metabolic risk in obese subjects.

Indexed as

AdultAgedBody CompositionCase-Control StudiesFemaleHairHumansInsulin ResistanceLogistic ModelsMiddle AgedMineralsObesitySerumTrace ElementsTriglyceridesMineralsTrace ElementsTriglyceridescopperinsulin resistancemetabolic syndromeobesityselenium

Identifiers

PMID34064348
PMCPMC8147795
OpenAlexW3159483737

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.