Evidence map›Paper›PMID 34064349›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

EEG and Sleep Effects of Tramadol Suggest Potential Antidepressant Effects with Different Mechanisms of Action.

Szabolcs Koncz, Noémi Papp, Noémi Menczelesz, Dóra Pothorszki, György Bagdy

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Szabolcs KonczDepartment of Pharmacodynamics, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0002-9465-945X
Noémi PappDepartment of Pharmacodynamics, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0001-9460-9391
Noémi MenczeleszDepartment of Pharmacodynamics, Semmelweis University, 1085 Budapest, Hungary.
Dóra PothorszkiDepartment of Pharmacodynamics, Semmelweis University, 1085 Budapest, Hungary.
György BagdyDepartment of Pharmacodynamics, Semmelweis University, 1085 Budapest, Hungary.
Semmelweis University · HU

Funding

Development of Scientific Workshops of Medical, Health Sciences and Pharmaceutical Educations EFOP-3.6.3-VEKOP-16-2017-00009Hungarian Brain Research Program 2017-1.2.1-NKP-2017-00002; KTIA_13_NAPA-II/14Ministry for Innovation and Technology in Hungary 2020-4.1.1.-TKP2020National Development Agency KTIA_NAP_13-1-2013-0001
6 · The paper itself

Abstract

Tramadol is a widely used, centrally acting, opioid analgesic compound, with additional inhibitory effects on the synaptic reuptake of serotonin and noradrenaline, as well as on the 5-HT

Indexed as

antidepressantbrain oscillationchronic paindepressionEEG power spectrapharmaco-EEGratsleepsleep-wake cycletramadol

Identifiers

PMID34064349
PMCPMC8147808
OpenAlexW3159718717

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.