Evidence mapPaperPMID 34064968Full record

Trial reportNutrients2021

Short-Term RCT of Increased Dietary Potassium from Potato or Potassium Gluconate: Effect on Blood Pressure, Microcirculation, and Potassium and Sodium Retention in Pre-Hypertensive-to-Hypertensive Adults.

Michael S Stone, Berdine R Martin, Connie M Weaver

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05994313 (STARchy Staples), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05994313 nacompletednot on this mapstarted 2023, after this paper: background citation

STARchy Staples: a Randomised Controlled Trial on Cardiometabolic Health

TypeinterventionalSponsorKing's College LondonRan2023 to 2025Enrolled71ConditionsCardiometabolic HealthArmsHabitual potato consumption, Habitual non-nutrient-dense staple consumption
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Approved Genetically Modified Potatoes (Journal of agricultural and food chemistry · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael S StoneNutrition Science, Purdue University, West Lafayette, IN 47907, USA.
Berdine R MartinNutrition Science, Purdue University, West Lafayette, IN 47907, USA.
Connie M WeaverNutrition Science, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-5450-9609
Purdue University West Lafayette · US

Funding

CSRD VA 1Delavau Pharmaceutical Partners 2
6 · The paper itself

Abstract

Increased potassium intake has been linked to improvements in cardiovascular and other health outcomes. We assessed increasing potassium intake through food or supplements as part of a controlled diet on blood pressure (BP), microcirculation (endothelial function), and potassium and sodium retention in thirty pre-hypertensive-to-hypertensive men and women. Participants were randomly assigned to a sequence of four 17 day dietary potassium treatments: a basal diet (control) of 60 mmol/d and three phases of 85 mmol/d added as potatoes, French fries, or a potassium gluconate supplement. Blood pressure was measured by manual auscultation, cutaneous microvascular and endothelial function by thermal hyperemia, utilizing laser Doppler flowmetry, and mineral retention by metabolic balance. There were no significant differences among treatments for end-of-treatment BP, change in BP over time, or endothelial function using a mixed-model ANOVA. However, there was a greater change in systolic blood pressure (SBP) over time by feeding baked/boiled potatoes compared with control (-6.0 mmHg vs. -2.6 mmHg;

Indexed as

GluconatesMicrocirculationPotassiumAdultBlood PressureCardiometabolic Risk FactorsCross-Over StudiesDietDietary SupplementsFecesFemaleHumansHypertensionMaleMiddle AgedPotassium, DietaryGluconatesPotassiumPotassium, DietarySodiumSodium Chloride, DietarySodium, Dietaryblood pressurecardiometabolic riskcontrolled feeding studymicrocirculationpotassiumretentionsodium

Identifiers

PMID34064968
PMCPMC8151047
OpenAlexW3163052078

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.