Evidence map›Paper›PMID 34065194›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis and α-Glucosidase Inhibition Activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2

Furqan Ahmad Saddique, Sana Aslam, Matloob Ahmad, Usman Ali Ashfaq, Muhammad Muddassar, Sadia Sultan, Saman Taj, Muzammil Hussain, Dae Sung Lee, Magdi E A Zaki

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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  5. Synthesis of NovelMolecules (Basel, Switzerland) · 2022
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  7. Identification of Cyclic Sulfonamides with anPharmaceuticals (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Furqan Ahmad SaddiqueDepartment of Chemistry, Government College University, Faisalabad 38000, Pakistan.
Sana AslamDepartment of Chemistry, Government College Women University, Faisalabad 38000, Pakistan.
Matloob AhmadDepartment of Chemistry, Government College University, Faisalabad 38000, Pakistan.ORCID 0000-0003-1302-8056
Usman Ali AshfaqDepartment of Bioinformatics and Biotechnology, Government College University, Faisalabad 38000, Pakistan.
Muhammad MuddassarDepartment of Biosciences, COMSATS University Islamabad, Park Road, Islamabad 45500, Pakistan.
Sadia SultanFaculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, Bandar Puncak Alam 42300, Selangor Darul Ehsan, Malaysia.
Saman TajDepartment of Bioinformatics and Biotechnology, Government College University, Faisalabad 38000, Pakistan.
Muzammil HussainDepartment of Environmental Engineering, Kyungpook National University, Daegu 41566, Korea.
Dae Sung LeeDepartment of Environmental Engineering, Kyungpook National University, Daegu 41566, Korea.
Magdi E A ZakiDepartment of Chemistry, Faculty of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.
Government College University, Faisalabad · PKKyungpook National University · KRCOMSATS University Islamabad · PKGovernment College Women University Faisalabad · PKImam Mohammad ibn Saud Islamic University · SAUniversiti Teknologi MARA · MY

Funding

Higher Education Commission of Pakistan NRPU-3715
6 · The paper itself

Abstract

Diabetes mellitus (DM) is a chronic disorder and has affected a large number of people worldwide. Insufficient insulin production causes an increase in blood glucose level that results in DM. To lower the blood glucose level, various drugs are employed that block the activity of the α-glucosidase enzyme, which is considered responsible for the breakdown of polysaccharides into monosaccharides leading to an increase in the intestinal blood glucose level. We have synthesized novel 2-(3-(benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2

Indexed as

AcetamidesComputer SimulationDiabetes MellitusDrug Evaluation, PreclinicalGlycoside Hydrolase InhibitorsHumansHypoglycemic AgentsInhibitory Concentration 50Molecular Docking SimulationStructure-Activity RelationshipThiazinesAcetamidesGlycoside Hydrolase InhibitorsHypoglycemic AgentsThiazines1,2-Benzothiazinesanti-diabeticmolecular dockingsynthesisα-glucosidase inhibition

Identifiers

PMID34065194
PMCPMC8161055
OpenAlexW3161535006

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.