Evidence map›Paper›PMID 34065593›Full record

ArticleInternational journal of molecular sciences2021

The Structure-Properties-Cytotoxicity Interplay: A Crucial Pathway to Determining Graphene Oxide Biocompatibility.

Marta Dziewięcka, Mirosława Pawlyta, Łukasz Majchrzycki, Katarzyna Balin, Sylwia Barteczko, Martyna Czerkawska, Maria Augustyniak

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Multigenerational Effects of Graphene Oxide Nanoparticles onInternational journal of molecular sciences · 2023
    Article
  12. Age- and Lifespan-Dependent Differences in GO Caused DNA Damage inInternational journal of molecular sciences · 2022
    Article
  13. Article
  14. Advances in Biologically Applicable Graphene-Based 2D Nanomaterials.International journal of molecular sciences · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marta DziewięckaInstitute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Bankowa 9, 40-007 Katowice, Poland.ORCID 0000-0001-9321-2579
Mirosława PawlytaDepartment of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of Technology, Konarskiego 18A, 44-100 Gliwice, Poland.ORCID 0000-0001-9072-3306
Łukasz MajchrzyckiCenter for Advanced Technology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 10, 61-614 Poznań, Poland.ORCID 0000-0001-5452-6399
Katarzyna BalinInstitute of Physics, University of Silesia, 75 Pulku Piechoty 1A, 41-500 Chorzow, Poland.ORCID 0000-0002-1811-3033
Sylwia BarteczkoInstitute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Bankowa 9, 40-007 Katowice, Poland.
Martyna CzerkawskaInstitute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Bankowa 9, 40-007 Katowice, Poland.
Maria AugustyniakInstitute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Bankowa 9, 40-007 Katowice, Poland.ORCID 0000-0003-1960-1669

Funding

Narodowe Centrum Nauki UMO-2020/37/B/NZ7/00570
6 · The paper itself

Abstract

Interest in graphene oxide nature and potential applications (especially nanocarriers) has resulted in numerous studies, but the results do not lead to clear conclusions. In this paper, graphene oxide is obtained by multiple synthesis methods and generally characterized. The mechanism of GO interaction with the organism is hard to summarize due to its high chemical activity and variability during the synthesis process and in biological buffers' environments. When assessing the biocompatibility of GO, it is necessary to take into account many factors derived from nanoparticles (structure, morphology, chemical composition) and the organism (species, defense mechanisms, adaptation). This research aims to determine and compare the in vivo toxicity potential of GO samples from various manufacturers. Each GO sample is analyzed in two concentrations and applied with food. The physiological reactions of an easy model

Indexed as

AnimalsApoptosisBiocompatible MaterialsCell SurvivalDNA DamageGraphiteGryllidaeNanoparticlesOxidation-ReductionOxidesBiocompatible Materialsgraphene oxideGraphiteOxidesbiocompatibilitygraphene oxide (GO)in vivo modelphysicochemical propertiestoxicity

Identifiers

PMID34065593
PMCPMC8161018

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.