Evidence map›Paper›PMID 34065985›Full record

ArticleViruses2021

Physical and Chemical Barriers in the Larval Midgut Confer Developmental Resistance to Virus Infection in

Simon Villegas-Ospina, David J Merritt, Karyn N Johnson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Regulating metabolism to shape immune function: Lessons from Drosophila.Seminars in cell & developmental biology · 2023
    Review
  4. The Intestinal Immune Defense System in Insects.International journal of molecular sciences · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Simon Villegas-OspinaFaculty of Science, School of Biological Sciences, The University of Queensland, Brisbane 4072, Australia.ORCID 0000-0002-0957-2596
David J MerrittFaculty of Science, School of Biological Sciences, The University of Queensland, Brisbane 4072, Australia.ORCID 0000-0002-8573-7508
Karyn N JohnsonFaculty of Science, School of Biological Sciences, The University of Queensland, Brisbane 4072, Australia.ORCID 0000-0001-8647-8985
The University of Queensland · AU

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
NIH HHS P40 OD018537
6 · The paper itself

Abstract

Insects can become lethally infected by the oral intake of a number of insect-specific viruses. Virus infection commonly occurs in larvae, given their active feeding behaviour; however, older larvae often become resistant to oral viral infections. To investigate mechanisms that contribute to resistance throughout the larval development, we orally challenged

Indexed as

AnimalsDicistroviridaeDigestive SystemDrosophilaFemaleHydrogen-Ion ConcentrationLarvaMaleVirus Diseasesantiviral mechanismsdicistrovirusDrosophilagut pHlarval developmentmidgutperitrophic matrix

Identifiers

PMID34065985
PMCPMC8151258
OpenAlexW3161747797

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.