Evidence map›Paper›PMID 34066528›Full record

ReviewJournal of clinical medicine2021

The Neuroimmune Role of Intestinal Microbiota in the Pathogenesis of Cardiovascular Disease.

Andrey V Suslov, Elizaveta Chairkina, Maria D Shepetovskaya, Irina S Suslova, Victoria A Khotina, Tatiana V Kirichenko, Anton Y Postnov

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Applied physiology: gut microbiota and antimicrobial therapy.European journal of applied physiology · 2024
    Review
  2. Article
  3. Microbiota: Not Just a Gut Feeling.Journal of clinical medicine · 2022
    Article
  4. Frontiers in microbiology · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Andrey V SuslovI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, 8-2 Trubetskaya Str., 119992 Moscow, Russia.ORCID 0000-0003-0613-8556
Elizaveta ChairkinaI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, 8-2 Trubetskaya Str., 119992 Moscow, Russia.
Maria D ShepetovskayaI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, 8-2 Trubetskaya Str., 119992 Moscow, Russia.
Irina S SuslovaCentral State Medical Academy of the Administrative Department of the President of the Russian Federation, 19-1A Marshal Timoshenko Str., 121359 Moscow, Russia.
Victoria A KhotinaResearch Institute of Human Morphology, 3 Tsyurupy Str., 117418 Moscow, Russia.ORCID 0000-0003-2096-3237
Tatiana V KirichenkoResearch Institute of Human Morphology, 3 Tsyurupy Str., 117418 Moscow, Russia.ORCID 0000-0002-2899-9202
Anton Y PostnovResearch Institute of Human Morphology, 3 Tsyurupy Str., 117418 Moscow, Russia.
Sechenov University · RUResearch Institute of Human Morphology · RUCentral State Medical Academy · RUResearch Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences · RU

Funding

Russian Science Foundation 20-15-00337
6 · The paper itself

Abstract

Currently, a bidirectional relationship between the gut microbiota and the nervous system, which is considered as microbiota-gut-brain axis, is being actively studied. This axis is believed to be a key mechanism in the formation of somatovisceral functions in the human body. The gut microbiota determines the level of activation of the hypothalamic-pituitary system. In particular, the intestinal microbiota is an important source of neuroimmune mediators in the pathogenesis of cardiovascular disease. This review reflects the current state of publications in PubMed and Scopus databases until December 2020 on the mechanisms of formation and participation of neuroimmune mediators associated with gut microbiota in the development of cardiovascular disease.

Indexed as

cardiovascular diseaseepithelial intestinal barrierhypothalamic-pituitary systemintestinal microbiota

Identifiers

PMID34066528
PMCPMC8124579
OpenAlexW3158091943

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.