Evidence map›Paper›PMID 34066967›Full record

ArticleCurrent issues in molecular biology2021

Vitamin D Deficiency Reduces Vascular Reactivity of Coronary Arterioles in Male Rats.

Zoltán Fontányi, Réka Eszter Sziva, Éva Pál, Leila Hadjadj, Anna Monori-Kiss, Eszter Mária Horváth, Rita Benkő, Attila Magyar, Andrea Heinzlmann, Zoltán Benyó and 3 more

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Current Knowledge of the Impact of Vitamin D in Coronary Artery Disease.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Zoltán FontányiDepartment of Obstetrics and Gynaecology, Semmelweis University, Üllői Street 78/a, 1082 Budapest, Hungary.
Réka Eszter SzivaDepartment of Obstetrics and Gynaecology, Semmelweis University, Üllői Street 78/a, 1082 Budapest, Hungary.ORCID 0000-0002-9170-4331
Éva PálDepartment of Translational Medicine, Semmelweis University, Üllői Street 78/a, 1082 Budapest, Hungary.ORCID 0000-0003-1793-1912
Leila HadjadjDepartment of Translational Medicine, Semmelweis University, Üllői Street 78/a, 1082 Budapest, Hungary.
Anna Monori-KissDepartment of Translational Medicine, Semmelweis University, Üllői Street 78/a, 1082 Budapest, Hungary.
Eszter Mária HorváthDepartment of Physiology, Semmelweis University, Tűzoltó Street 37-47, 1094 Budapest, Hungary.
Rita BenkőDepartment of Physiology, Semmelweis University, Tűzoltó Street 37-47, 1094 Budapest, Hungary.ORCID 0000-0001-7740-9128
Attila MagyarDepartment of Anatomy, Histology and Embriology, Semmelweis University, Tűzoltó Street 58, 1094 Budapest, Hungary.
Andrea HeinzlmannDepartment of Anatomy and Histology, University of Veterinary Medicine, István Street 2, 1078 Budapest, Hungary.
Zoltán BenyóDepartment of Translational Medicine, Semmelweis University, Üllői Street 78/a, 1082 Budapest, Hungary.ORCID 0000-0001-6015-0359
György L NádasyDepartment of Physiology, Semmelweis University, Tűzoltó Street 37-47, 1094 Budapest, Hungary.ORCID 0000-0003-2057-2391
Gabriella MassziDepartment of Internal Medicine, National Institute of Mental Health, Neurology and Neurosurgery, Lehel Street 59-61, 1135 Budapest, Hungary.
Szabolcs VárbíróDepartment of Obstetrics and Gynaecology, Semmelweis University, Üllői Street 78/a, 1082 Budapest, Hungary.
Semmelweis University · HUUniversity of Veterinary Medicine · HU

Funding

Dean of the Medical Faculty, Semmelweis University 2016/8Hungarian Hypertension Society 2015/1Semmelweis Science and Innovation Fund STIA-KF-17
6 · The paper itself

Abstract

backgroundVitamin D deficiency (VDD) may be considered an independent cardiovascular (CV) risk factor, and it is well known that CV risk is higher in males. Our goal was to investigate the pharmacological reactivity and receptor expression of intramural coronary artery segments of male rats in cases of different vitamin D supply.

methodsFour-week-old male Wistar rats were divided into a control group (

resultsThromboxane A

conclusionsVD-deficient male coronary arteries showed deteriorated pharmacological reactivity to TXA

Indexed as

AndrogensAnimalsArteriolesCoronary Artery DiseaseDisease Models, AnimalEstradiolEstrogensMaleRatsRats, WistarReceptors, ThromboxaneTestosteroneThromboxane A2VasoconstrictionVitamin D DeficiencyAndrogensEstradiolEstrogensReceptors, ThromboxaneTestosteroneThromboxane A2cardiovascular diseaseestradiolmalepharmacological reactivityrat modeltestosteronethromboxanevitamin D deficiency

Identifiers

PMID34066967
PMCPMC8928984
OpenAlexW3158903974

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.