Evidence map›Paper›PMID 34067055›Full record

ArticleNutrients2021

Fasting: How to Guide.

Alda Attinà, Claudia Leggeri, Rita Paroni, Francesca Pivari, Michele Dei Cas, Alessandra Mingione, Maria Dri, Marco Marchetti, Laura Di Renzo

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Intermittent fasting enhances cancer therapyWorld journal of clinical oncology · 2026
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  19. [Lipedema pain-the neglected symptom].Dermatologie (Heidelberg, Germany) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Alda AttinàSchool of Specialization in Food Sciences, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Claudia LeggeriSchool of Specialization in Food Sciences, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Rita ParoniDepartment of Health Sciences, University of Milan, Via A. di Rudinì, 8, 20142 Milan, Italy.ORCID 0000-0002-3186-8860
Francesca PivariDepartment of Health Sciences, University of Milan, Via A. di Rudinì, 8, 20142 Milan, Italy.ORCID 0000-0002-2277-6833
Michele Dei CasDepartment of Health Sciences, University of Milan, Via A. di Rudinì, 8, 20142 Milan, Italy.ORCID 0000-0001-7359-8558
Alessandra MingioneDepartment of Health Sciences, University of Milan, Via A. di Rudinì, 8, 20142 Milan, Italy.
Maria DriPhD School of Applied Medical-Surgical Sciences, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Marco MarchettiPhD School of Applied Medical-Surgical Sciences, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Laura Di RenzoSection of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0001-8875-6723
University of Rome Tor Vergata · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fasting potentials are the most interesting topics in the Nutritional Era. Fasting consists of the catabolism of lipids, proteins, and carbohydrates to maintain blood glucose levels in a normal range. The action mechanisms of fasting were firstly understood in minor organisms and later in humans. Nutritional interventions of caloric restriction could attenuate age-associated epigenetic alterations and could have a protective effect against cellular alterations, promoting longevity and health span. While most fasting studies point out the weight and fat mass decreases, it is important to define specific guidelines for fasting and non-fasting days to enhance adherence, minimize the dropout rates of the interventions, and maximize body composition improvement. Although the panorama of evidence on fasting and caloric restriction is wide, there is a lack of a safe fasting protocol to guide physicians in its prescription. The main goal is to identify a how to use guide, a major posology of fasting, inserted within a huge dietetic personalized strategy leading to an optimal and healthy nutritional status.

Indexed as

Practice Guidelines as TopicBody CompositionCaloric RestrictionDieteticsFastingHumansLongevityanti-inflammatory dietbody compositioncaloric restrictiondietfastinglongevityMediterranean modelpersonalized nutritionstarvation

Identifiers

PMID34067055
PMCPMC8151159
OpenAlexW3158863045

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.