Evidence map›Paper›PMID 34067107›Full record

ArticleMolecules (Basel, Switzerland)2021

Protective Effects of Swertiamarin against Methylglyoxal-Induced Epithelial-Mesenchymal Transition by Improving Oxidative Stress in Rat Kidney Epithelial (NRK-52E) Cells.

Kirti Parwani, Farhin Patel, Dhara Patel, Palash Mandal

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  7. Phenolic Compounds fromMolecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kirti ParwaniDepartment of Biological Sciences, P. D. Patel Institute of Applied Sciences, Charotar University of Science and Technology, Changa 388421, India.
Farhin PatelDepartment of Biological Sciences, P. D. Patel Institute of Applied Sciences, Charotar University of Science and Technology, Changa 388421, India.
Dhara PatelDepartment of Biological Sciences, P. D. Patel Institute of Applied Sciences, Charotar University of Science and Technology, Changa 388421, India.ORCID 0000-0002-2817-6986
Palash MandalDepartment of Biological Sciences, P. D. Patel Institute of Applied Sciences, Charotar University of Science and Technology, Changa 388421, India.ORCID 0000-0001-6612-3773
Charotar University of Science and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased blood glucose in diabetic individuals results in the formation of advanced glycation end products (AGEs), causing various adverse effects on kidney cells, thereby leading to diabetic nephropathy (DN). In this study, the antiglycative potential of Swertiamarin (SM) isolated from the methanolic extract of

Indexed as

AnimalsCattleCell ShapeCell SurvivalChromatography, High Pressure LiquidEndoplasmic Reticulum StressEpithelial CellsEpithelial-Mesenchymal TransitionFluorescenceFructoseGlycation End Products, AdvancedGlycosylationInflammationIridoid GlucosidesKidneyLigandsAger protein, ratargpyrimidineFructoseGlycation End Products, AdvancedIridoid GlucosidesLigandsMalondialdehydeOrnithineProtective AgentsPyrimidinesPyronesPyruvaldehydeReactive Oxygen SpeciesReceptor for Advanced Glycation End ProductsSerum Albumin, Bovineswertiamarinadvanced glycation end product (AGE)AGE-inhibitordiabetic nephropathyepithelial to mesenchymal transitionoxidative stressswertiamarin

Identifiers

PMID34067107
PMCPMC8125635
OpenAlexW3159915470

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.