Evidence map›Paper›PMID 34067499›Full record

ReviewMarine drugs2021

Applications of Marine Organism-Derived Polydeoxyribonucleotide: Its Potential in Biomedical Engineering.

Tae-Hee Kim, Seong-Yeong Heo, Gun-Woo Oh, Soo-Jin Heo, Won-Kyo Jung

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Rainbow Trout (Genes · 2025
    Article
  9. Polynucleotide Mixture Attenuates Ultraviolet B-Induced Skin Pigmentation.International journal of molecular sciences · 2025
    Article
  10. Review
  11. Article
  12. Review of Preclinical and Clinical Studies Supporting the Role of Polydeoxyribonucleotide in the Treatment of Tendon Disorders.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tae-Hee KimDepartment of Biomedical Engineering and New-Senior Healthcare Innovation Center (BK21 Plus), Pukyong National University, Busan 48513, Korea.ORCID 0000-0002-0988-0193
Seong-Yeong HeoResearch Center for Marine Integrated Bionics Technology, Pukyong National University, Busan 48513, Korea.
Gun-Woo OhResearch Center for Marine Integrated Bionics Technology, Pukyong National University, Busan 48513, Korea.
Soo-Jin HeoJeju Marine Research Center, Korea Institute of Ocean Science & Technology (KIOST), Jeju 63349, Korea.
Won-Kyo JungDepartment of Biomedical Engineering and New-Senior Healthcare Innovation Center (BK21 Plus), Pukyong National University, Busan 48513, Korea.ORCID 0000-0002-1615-750X
Korea Institute of Ocean Science and Technology · KRPukyong National University · KR

Funding

National Research Foundation of Korea 2019R1A2C1007218
6 · The paper itself

Abstract

Polydeoxyribonucleotides (PDRNs) are a family of DNA-derived drugs with a molecular weight ranging from 50 to 1500 kDa, which are mainly extracted from the sperm cells of salmon trout or chum salmon. Many pre-clinical and clinical studies have demonstrated the wound healing and anti-inflammatory properties of PDRN, which are mediated by the activation of adenosine A

Indexed as

Biomedical EngineeringOncorhynchusPolydeoxyribonucleotidesAnimalsAquatic OrganismsHumansPolydeoxyribonucleotidesbiomedical engineeringmarine organismspolydeoxyribonucleotide

Identifiers

PMID34067499
PMCPMC8224764
OpenAlexW3164729721

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.