Evidence mapPaperPMID 34068182Full record

ArticleJournal of clinical medicine2021

Multi-Omics Analysis of Anti-Inflammatory Action of Alkaline Extract of the Leaves of

Hiroshi Sakagami, Sachie Nakatani, Ayame Enomoto, Sana Ota, Miku Kaneko, Masahiro Sugimoto, Misaki Horiuchi, Kazuki Toeda, Takaaki Oizumi

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Inhibition ofPathogens (Basel, Switzerland) · 2026
    Article
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  6. Quantification ofIn vivo (Athens, Greece)
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Hiroshi SakagamiMeikai University Research Institute of Odontology (M-RIO), Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, Japan.ORCID 0000-0001-8001-2121
Sachie NakataniGraduate School of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan.
Ayame EnomotoInstitute for Advanced Biosciences, Keio University, Tsuruoka 997-0052, Japan.
Sana OtaInstitute for Advanced Biosciences, Keio University, Tsuruoka 997-0052, Japan.
Miku KanekoInstitute for Advanced Biosciences, Keio University, Tsuruoka 997-0052, Japan.
Masahiro SugimotoInstitute for Advanced Biosciences, Keio University, Tsuruoka 997-0052, Japan.ORCID 0000-0003-3316-2543
Misaki HoriuchiDaiwa Biological Research Institute Co., Ltd., Sakado 3-2-1, Takatsu-ku, Kawasaki, Kanagawa 213-0012, Japan.
Kazuki ToedaDaiwa Biological Research Institute Co., Ltd., Sakado 3-2-1, Takatsu-ku, Kawasaki, Kanagawa 213-0012, Japan.
Takaaki OizumiDaiwa Biological Research Institute Co., Ltd., Sakado 3-2-1, Takatsu-ku, Kawasaki, Kanagawa 213-0012, Japan.
Keio University · JPJosai University · JPMeikai University · JPTokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efficient utilization of alkaline extracts of several plants for the treatment of oral diseases has been reported. To investigate the mechanism of anti-inflammatory activity of alkaline extract of the leaves of

Indexed as

alkaline extract of the leaves of Sasa sp.anti-inflammationapoptosiscell survivalDNA arrayhuman gingival fibroblastIL-1βmetabolomicsPGE2

Identifiers

PMID34068182
PMCPMC8152990
OpenAlexW3162443136

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.