ReviewMolecules (Basel, Switzerland)2021
The Different Facets of Triclocarban: A Review.
Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Are Wild Boars Exposed to Triclosan and Triclocarban?Animals : an open access journal from MDPI · 2026Article
- When Disinfection Fails: Biocide Tolerance as a Driver ofAntibiotics (Basel, Switzerland) · 2026Review
- Identification of osteoarthritis-related genes and potential drugs based on single cell RNA-seq data.Molecular medicine (Cambridge, Mass.) · 2025Article
- Flurbiprofen restores rifampicin and isoniazid sensitivity in multidrug-resistant Mycobacterium tuberculosis putatively by inhibiting efflux pumps Rv0194 and Rv0933.Folia microbiologica · 2025Article
- Thermodynamic Study of the Solubility of Triclocarban in Polyethylene Glycol 200 + Water Cosolvent Mixtures at Different Temperatures.Molecules (Basel, Switzerland) · 2025Article
- Spatial metabolomics reveal metabolic alternations in the injured mice kidneys induced by triclocarban treatment.Journal of pharmaceutical analysis · 2024Article
- An assessment and characterization of pharmaceuticals and personal care products (PPCPs) within the Great Lakes Basin: Mussel Watch Program (2013-2018).Environmental monitoring and assessment · 2024Article
- The Ongoing Impact of COVID-19 on Pediatric Obesity.Pediatric reports · 2024Review
- Computational Design of Novel Griseofulvin Derivatives Demonstrating Potential Antibacterial Activity: Insights from Molecular Docking and Molecular Dynamics Simulation.International journal of molecular sciences · 2024Article
- The use ofFrontiers in toxicology · 2024Article
- Article
- The Potential for Genotoxicity, Mutagenicity and Endocrine Disruption in Triclosan and Triclocarban Assessed through a Combination of In Vitro Methods.Journal of xenobiotics · 2023Article
- Thermodynamic Assessment of Triclocarban Dissolution Process inMolecules (Basel, Switzerland) · 2023Article
- Review
- Personal Care Products as a Contributing Factor to Antimicrobial Resistance: Current State and Novel Approach to Investigation.Antibiotics (Basel, Switzerland) · 2023Review
- Sustainable Secondary-Raw Materials, Natural Substances and Eco-Friendly Nanomaterial-Based Approaches for Improved Surface Performances: An Overview of What They Are and How They Work.International journal of molecular sciences · 2023Review
- Diarylureas: New Promising Small Molecules againstAntibiotics (Basel, Switzerland) · 2023Review
- Thidiazuron: New Trends and Future Perspectives to FightAntibiotics (Basel, Switzerland) · 2022Review
- Triclosan: A Small Molecule with Controversial Roles.Antibiotics (Basel, Switzerland) · 2022Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the late 1930s and early 1940s, it was discovered that the substitution on aromatic rings of hydrogen atoms with chlorine yielded a novel chemistry of antimicrobials. However, within a few years, many of these compounds and formulations showed adverse effects, including human toxicity, ecotoxicity, and unwanted environmental persistence and bioaccumulation, quickly leading to regulatory bans and phase-outs. Among these, the triclocarban, a polychlorinated aromatic antimicrobial agent, was employed as a major ingredient of toys, clothing, food packaging materials, food industry floors, medical supplies, and especially of personal care products, such as soaps, toothpaste, and shampoo. Triclocarban has been widely used for over 50 years, but only recently some concerns were raised about its endocrine disruptive properties. In September 2016, the U.S. Food and Drug Administration banned its use in over-the-counter hand and body washes because of its toxicity. The withdrawal of triclocarban has prompted the efforts to search for new antimicrobial compounds and several analogues of triclocarban have also been studied. In this review, an examination of different facets of triclocarban and its analogues will be analyzed.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.