Evidence map›Paper›PMID 34068819›Full record

ReviewCells2021

Shaping of T Cell Functions by Trogocytosis.

Masafumi Nakayama, Arisa Hori, Saori Toyoura, Shin-Ichiro Yamaguchi

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 44 citations in OpenAlex.

  1. Macrophage Trogocytosis of Tumor Cells Drives the Immunosuppression of Tumor Microenvironment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Trogocytosis in cancer immunity and cellular immunotherapy: mechanisms, therapeutic challenges, and translational opportunities.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Frontiers in cellular neuroscience · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. The Biological Significance of Trogocytosis.Results and problems in cell differentiation · 2024
    Article
  18. The origin of human CD20Frontiers in immunology · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Masafumi NakayamaLaboratory of Immunology and Microbiology, College of Pharmaceutical Sciences, Ritsumeikan University, Shiga 525-8577, Japan.
Arisa HoriLaboratory of Immunology and Microbiology, College of Pharmaceutical Sciences, Ritsumeikan University, Shiga 525-8577, Japan.
Saori ToyouraLaboratory of Immunology and Microbiology, College of Pharmaceutical Sciences, Ritsumeikan University, Shiga 525-8577, Japan.
Shin-Ichiro YamaguchiLaboratory of Immunology and Microbiology, College of Pharmaceutical Sciences, Ritsumeikan University, Shiga 525-8577, Japan.
Ritsumeikan University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trogocytosis is an active process whereby plasma membrane proteins are transferred from one cell to the other cell in a cell-cell contact-dependent manner. Since the discovery of the intercellular transfer of major histocompatibility complex (MHC) molecules in the 1970s, trogocytosis of MHC molecules between various immune cells has been frequently observed. For instance, antigen-presenting cells (APCs) acquire MHC class I (MHCI) from allografts, tumors, and virally infected cells, and these APCs are subsequently able to prime CD8

Indexed as

AnimalsAntigen PresentationAntigensBlood ProteinsCD8-Positive T-LymphocytesDendritic CellsHistocompatibility Antigens Class IHistocompatibility Antigens Class IIHumansImmune SystemImmunological SynapsesInflammationLymphocyte ActivationMajor Histocompatibility ComplexMiceNeoplasmsAntigensBlood ProteinsHistocompatibility Antigens Class IHistocompatibility Antigens Class IIReceptors, Chimeric Antigenacquisitionchimeric antigen receptor (CAR)cross-dressedcross-presentationdendritic cell (DC)escape variantfratricidenibblingstrippingTCRTreg

Identifiers

PMID34068819
PMCPMC8151334
OpenAlexW3160484119

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.