Evidence map›Paper›PMID 34070714›Full record

SynthesisInternational journal of environmental research and public health2021

Prevalence of Type 2 Diabetes in South Africa: A Systematic Review and Meta-Analysis.

Carmen Pheiffer, Victoria Pillay-van Wyk, Eunice Turawa, Naomi Levitt, Andre P Kengne, Debbie Bradshaw

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05755555 (Testing the Effectiveness of Different Messaging Approaches to Increase Doctor Visits to Confirm or Exclude a Diagnosis of Prediabetes or Diabetes Amongst Individuals With Risk Factors for Diabetes), which is not on this map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05755555 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Testing the Effectiveness of Different Messaging Approaches to Increase Doctor Visits to Confirm or Exclude a Diagnosis of Prediabetes or Diabetes Amongst Individuals With Risk Factors for Diabetes: A Randomised, Controlled Trial

TypeinterventionalSponsorWits Health Consortium (Pty) LtdRan2022 to 2023Enrolled5,000ConditionsType 2 Diabetes, Pre-diabetesArmsVisit a doctor
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Review
  9. Clinical and microbiological epidemiology ofJAC-antimicrobial resistance · 2026
    Article
  10. Dual PTP1B/DPP4 Inhibitory Potential ofComputational and structural biotechnology journal · 2026
    Article
  11. Article
  12. Article
  13. Diabetes knowledge levels among patients in Mhlontlo, South Africa: A quantitative study.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carmen PheifferBiomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg 7505, South Africa.ORCID 0000-0002-0707-1552
Victoria Pillay-van WykBurden of Disease Research Unit, South African Medical Research Council, Tygerberg 7505, South Africa.
Eunice TurawaBurden of Disease Research Unit, South African Medical Research Council, Tygerberg 7505, South Africa.ORCID 0000-0003-3722-1547
Naomi LevittDepartment of Medicine, Division of Endocrinology, University of Cape Town, Observatory 7925, South Africa.
Andre P KengneNon-Communicable Diseases Research Unit, South African Medical Research Council, Tygerberg 7505, South Africa.ORCID 0000-0002-5183-131X
Debbie BradshawBurden of Disease Research Unit, South African Medical Research Council, Tygerberg 7505, South Africa.ORCID 0000-0002-3588-2184

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthesis of existing prevalence data using rigorous systematic review methods is considered an effective strategy to generate representative and robust prevalence figures to inform health planning and policy. The purpose of this systematic review was to identify, collate, and synthesise all studies reporting the prevalence of total and newly diagnosed type 2 diabetes (T2DM), impaired glucose tolerance (IGT), and impaired fasting glucose (IFG) in South Africa. Four databases, PubMed, Scopus, Web of Science, and African Index Medicus were searched for articles published between January 1997 and June 2020. A total of 1886 articles were identified, of which 11 were included in the meta-analysis. The pooled prevalence in individuals 25 years and older was 15.25% (11.07-19.95%) for T2DM, 9.59% (5.82-14.17%) for IGT, 3.55% (0.38-9.61%) for IFG, and 8.29% (4.97-12.34%) for newly diagnosed T2DM. Although our pooled estimate may be imprecise due to significant heterogeneity across studies with regard to population group, age, gender, setting, diagnostic test, and study design, we provide evidence that the burden of glucose intolerance in South Africa is high. These factors contribute to the paucity of representative T2DM prevalence data. There is a need for well-designed epidemiological studies that use best-practice and standardised methods to assess prevalence.

Indexed as

Diabetes Mellitus, Type 2Glucose IntolerancePrediabetic StateBlood GlucoseHumansPrevalenceSouth AfricaBlood Glucoseimpaired fasting glucoseimpaired glucose tolerancenewly diagnosed diabetesprevalenceSouth Africatype 2 diabetes mellitus

Identifiers

PMID34070714
PMCPMC8199430

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.