Evidence map›Paper›PMID 34070821›Full record

SynthesisMarine drugs2021

Algae-Derived Anti-Inflammatory Compounds against Particulate Matters-Induced Respiratory Diseases: A Systematic Review.

Pek Xyen Tan, Krishnapriya Thiyagarasaiyar, Cheng-Yau Tan, You-Jin Jeon, Mohd Shahrul Mohd Nadzir, Yong-Jiang Wu, Liang-Ee Low, Atanas G Atanasov, Long Chiau Ming, Kai Bin Liew and 2 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Methyl alcohol extract of marine green algaNutrition research and practice · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 6 countries.

Pek Xyen TanDepartment of Biological Sciences, School of Medical and Life Sciences, Sunway University, Subang Jaya 47500, Malaysia.ORCID 0000-0002-4907-6132
Krishnapriya ThiyagarasaiyarDepartment of Biological Sciences, School of Medical and Life Sciences, Sunway University, Subang Jaya 47500, Malaysia.
Cheng-Yau TanDepartment of Biological Sciences, School of Medical and Life Sciences, Sunway University, Subang Jaya 47500, Malaysia.
You-Jin JeonDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Korea.ORCID 0000-0003-3299-7266
Mohd Shahrul Mohd NadzirDepartment of Earth Sciences and Environmental, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Malaysia.ORCID 0000-0003-0925-3998
Yong-Jiang WuCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0003-0246-9067
Liang-Ee LowCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Atanas G AtanasovLudwig Boltzmann Institute of Digital Health and Patient Safety, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-2545-0967
Long Chiau MingPAP Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong BE1410, Brunei.ORCID 0000-0002-6971-1383
Kai Bin LiewFaculty of Pharmacy, University of Cyberjaya, Cyberjaya 63000, Malaysia.
Bey-Hing GohCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0003-1006-3649
Yoon-Yen YowDepartment of Biological Sciences, School of Medical and Life Sciences, Sunway University, Subang Jaya 47500, Malaysia.ORCID 0000-0002-3859-2094
Sunway University · MYMonash University Malaysia · MYJeju National University · KRNational University of Malaysia · MYUniversiti Brunei Darussalam · BNUniversity of Cyberjaya · MYUniversity of Vienna · ATZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Air pollution has recently become a subject of increasing concern in many parts of the world. The World Health Organization (WHO) estimated that nearly 4.2 million early deaths are due to exposure to fine particles in polluted air, which causes multiple respiratory diseases. Algae, as a natural product, can be an alternative treatment due to potential biofunctional properties and advantages. This systematic review aims to summarize and evaluate the evidence of metabolites derived from algae as potential anti-inflammatory agents against respiratory disorders induced by atmospheric particulate matter (PM). Databases such as Scopus, Web of Science, and PubMed were systematically searched for relevant published full articles from 2016 to 2020. The main key search terms were limited to "algae", "anti-inflammation", and "air pollutant". The search activity resulted in the retrieval of a total of 36 publications. Nine publications are eligible for inclusion in this systematic review. A total of four brown algae (

Indexed as

PhaeophyceaeAir PollutantsAnimalsAnti-Inflammatory AgentsHumansParticulate MatterRespiratory Tract DiseasesAir PollutantsAnti-Inflammatory AgentsParticulate Matteralgaeanti-inflammationparticulate matterrespiratory diseases

Identifiers

PMID34070821
PMCPMC8227865
OpenAlexW3165068233

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.