Evidence map›Paper›PMID 34073395›Full record

SynthesisGenes2021

Origin, Evolution and Stability of Overlapping Genes in Viruses: A Systematic Review.

Angelo Pavesi

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

  1. The diverse functions of viral microproteins.bioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Cellular function of the GndA microprotein during heat shock.bioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Creation of the HIV-1 antisense geneMicrobiology spectrum · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Hepatitis B and circadian rhythm of the liver.World journal of gastroenterology · 2022
    Review
  19. A 336-nucleotide in-frame deletion in ORF7a gene of SARS-CoV-2 identified in genomic surveillance by next-generation sequencing.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Angelo PavesiDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 23/A, I-43124 Parma, Italy.
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During their long evolutionary history viruses generated many proteins

Indexed as

Mutation RateGenes, ViralPhylogenySelection, GeneticVirusesasymmetric evolutioncodon usagede novo protein creationmodular evolutionmultivariate statisticsnegative selection: phylogenetic distributionpositive selectionprediction methodssequence-composition featuressymmetric evolutionvirus evolution

Identifiers

PMID34073395
PMCPMC8227390
OpenAlexW3165064040

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.