Evidence map›Paper›PMID 34073995›Full record

ReviewInternational journal of molecular sciences2021

Latency Reversing Agents: Kick and Kill of HTLV-1?

Annika P Schnell, Stephan Kohrt, Andrea K Thoma-Kress

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Tumor Antigens beyond the Human Exome.International journal of molecular sciences · 2024
    Review
  9. Review
  10. Mcl-1 Protein and Viral Infections: A Narrative Review.International journal of molecular sciences · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Design and Synthesis of Hybrid Compounds as Epigenetic Modifiers.Pharmaceuticals (Basel, Switzerland) · 2021
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Annika P SchnellFAU Junior Research Group "Retroviral Pathogenesis" and BMBF Junior Research Group in Infection Research "Milk Transmission of Viruses", Institute of Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.ORCID 0000-0003-3808-2091
Stephan KohrtFAU Junior Research Group "Retroviral Pathogenesis" and BMBF Junior Research Group in Infection Research "Milk Transmission of Viruses", Institute of Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Andrea K Thoma-KressFAU Junior Research Group "Retroviral Pathogenesis" and BMBF Junior Research Group in Infection Research "Milk Transmission of Viruses", Institute of Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.ORCID 0000-0002-8568-9526
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

Bundesministerium für Bildung und Forschung "Milk-TV" (01KI2023),Deutsche Forschungsgemeinschaft project number 401821119, GRK2504, Subproject A2Interdisciplinary Center for Clinical Research at the Medical Faculty of the Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg A91
6 · The paper itself

Abstract

Human T-cell leukemia virus type 1 (HTLV-1), the cause of adult T-cell leukemia/lymphoma (ATLL), is a retrovirus, which integrates into the host genome and persistently infects CD4

Indexed as

CD4-Positive T-LymphocytesGene Expression Regulation, ViralGene Products, taxHistone Deacetylase InhibitorsHistonesHumansHuman T-lymphotropic virus 1Leukemia-Lymphoma, Adult T-CellPhosphorylationPositive Transcriptional Elongation Factor BVirus LatencyGene Products, taxHistone Deacetylase InhibitorsHistonesPositive Transcriptional Elongation Factor BATLLHDAC-inhibitor (HDACi)HIVHTLV-1kick and killlatencylatency reversing agents (LRA)P-TEFbshock and killTax

Identifiers

PMID34073995
PMCPMC8197370
OpenAlexW3165753306

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.