ArticleCell stress & chaperones2021
Dynamic changes in blood immune cell composition and function in Holstein and Jersey steers in response to heat stress.
Article in Cell stress & chaperones, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 44 citations in OpenAlex.
- Initiation of immune checkpoint inhibitor therapy in winter is associated with improved overall survival in patients with advanced non-small cell lung cancer.Oncology letters · 2026Article
- Comparative study of hematological responses to thermal stress in Sahiwal and Hardhenu calves.Tropical animal health and production · 2026Article
- Generation-Specific Heterosis in Lactation, Reproduction, and Blood Transcriptomic Profiles of Chinese Simmental × Holstein Crossbred Cows.Animals : an open access journal from MDPI · 2026Article
- Effect of environmental temperature on oxidative status, inflammatory response and endocannabinoid system at oestrus in dairy cows.Veterinary record open · 2026Article
- A new type of biomarker for heat stress: insights from immunology.Frontiers in immunology · 2026Review
- Comparative Analysis of the Effects of Mogroside V, Epigallocatechin Gallate, and Resveratrol on Growth Performance, Blood Parameters, Rumen Microbiota, and Short-Chain Fatty Acid Metabolism in Heat-Stressed Hu Sheep.Food science & nutrition · 2026Article
- Understanding Climate Change Threats to Vertebrate Wildlife by Studying Ecoimmunology Across Biological Scales.Integrative and comparative biology · 2025Review
- Effect of heat stress on some serum and reproductive parameters of Holstein dairy cows in Egypt: potential biomarkers.BMC veterinary research · 2025Article
- Identification of Thermoneutral Zone in Sahiwal Zebu Calves in Subtropical Climate of India.Animals : an open access journal from MDPI · 2025Article
- Analysis of Bacterial Diversity in Jersey Cow Colostrum and Mature Milk and the Study of the Probiotic Functions ofFood science & nutrition · 2025Article
- Multi-Omics Analysis of Chronic Heat Stress-Induced Biological Effects, Liver Injury, and Heat Tolerance Mechanisms via Oxidative and Anti-Inflammatory Pathways in Early-Pregnancy Sows.Antioxidants (Basel, Switzerland) · 2025Article
- Effects of Climate Change on the Immune System: A Narrative Review.Health science reports · 2025Article
- Integrated analysis of rumen metabolomics and metataxonomics to understand changes in metabolic and microbial community in Korean native goats under heat stress.Scientific reports · 2024Article
- Skin transcriptomic analysis reveals candidate genes and pathways associated with thermotolerance in hair sheep.International journal of biometeorology · 2024Article
- Article
- Review of the Heat Stress-Induced Responses in Dairy Cattle.Animals : an open access journal from MDPI · 2023Review
- Genome-wide expression analysis reveals different heat shock responses in indigenous (Bos indicus) and crossbred (Bos indicus X Bos taurus) cattle.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2023Article
- Candidate genes associated with heat stress and breeding strategies to relieve its effects in dairy cattle: a deeper insight into the genetic architecture and immune response to heat stress.Frontiers in veterinary science · 2023Review
- Metabolomic and transcriptomic study to understand changes in metabolic and immune responses in steers under heat stress.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Article
- Effect of Cooling Blanket on the Heat Stress of Horses in Hot and Humid Environments.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
Heat stress has detrimental effects on livestock via diverse immune and physiological changes; heat-stressed animals are rendered susceptible to diverse diseases. However, there is relatively little information available regarding the altered immune responses of domestic animals in heat stress environments, particularly in cattle steers. This study aimed to determine the changes in the immune responses of Holstein and Jersey steers under heat stress. We assessed blood immune cells and their functions in the steers of two breeds under normal and heat stress conditions and found that immune cell proportions and functions were altered in response to different environmental conditions. Heat stress notably reduced the proportions of CD21
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.