Evidence map›Paper›PMID 34082409›Full record

ArticleJournal of neural engineering2021

Chondroitinase ABC/galectin-3 fusion proteins with hyaluronan-based hydrogels stabilize enzyme and provide targeted enzyme activity for neural applications.

Nora Hlavac, Dillon T Seroski, Nikunj K Agrawal, Leilani Astrab, Renjie Liu, Gregory A Hudalla, Christine E Schmidt

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neural engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nora HlavacJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.ORCID 0000-0001-7246-374X
Dillon T SeroskiJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.
Nikunj K AgrawalJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.
Leilani AstrabJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.
Renjie LiuJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.
Gregory A HudallaJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.
Christine E SchmidtJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.ORCID 0000-0002-5865-6016
University of Florida · US

Funding

Functionalized Enzyme Treatments for Dual-Targeting of Inflammation in Spinal Cord InjuryR21NS123596 · NINDS · UNIVERSITY OF FLORIDA · PI KESELOWSKY, BENJAMIN GEORGE, SCHMIDT, CHRISTINE E · 2021 to 2021
$410k
NINDS NIH HHS R21 NS123596
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chondroitin ABC LyaseSpinal Cord InjuriesAnimalsGalectin 3Hyaluronic AcidHydrogelsRatsRats, Sprague-DawleyChondroitin ABC LyaseGalectin 3Hyaluronic AcidHydrogelscentral nervous system injuryDRG outgrowthglial scarhyaluronanneural regenerationspinal cord injury

Identifiers

PMID34082409
PMCPMC12900259
OpenAlexW3165033051

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.