Evidence map›Paper›PMID 34095146›Full record

ArticleFrontiers in cell and developmental biology2021

Loss of Pde6a Induces Rod Outer Segment Shrinkage and Visual Alterations in

Lucie Crouzier, Camille Diez, Elodie M Richard, Nicolas Cubedo, Clément Barbereau, Mireille Rossel, Thomas Delaunay, Tangui Maurice, Benjamin Delprat

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Models of Photoreceptor Degeneration in Adult Zebrafish.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  3. Article
  4. Article
  5. Transcriptome Profiling of Etridiazole-Exposed Zebrafish (International journal of molecular sciences · 2023
    Article
  6. An Overview towards Zebrafish Larvae as a Model for Ocular Diseases.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Zebrafish models of inherited retinal dystrophies.Journal of translational genetics and genomics · 2022
    Article
  11. Use of Zebrafish Models to Boost Research in Rare Genetic Diseases.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Lucie CrouzierMMDN, Univ Montpellier, EPHE, INSERM, Montpellier, France.
Camille DiezMMDN, Univ Montpellier, EPHE, INSERM, Montpellier, France.
Elodie M RichardMMDN, Univ Montpellier, EPHE, INSERM, Montpellier, France.
Nicolas CubedoMMDN, Univ Montpellier, EPHE, INSERM, Montpellier, France.
Clément BarbereauMMDN, Univ Montpellier, EPHE, INSERM, Montpellier, France.
Mireille RosselMMDN, Univ Montpellier, EPHE, INSERM, Montpellier, France.
Thomas DelaunayIES, Univ Montpellier, CNRS, Montpellier, France.
Tangui MauriceMMDN, Univ Montpellier, EPHE, INSERM, Montpellier, France.
Benjamin DelpratMMDN, Univ Montpellier, EPHE, INSERM, Montpellier, France.
Inserm · FRUniversité de Montpellier · FRÉcole Pratique des Hautes Études · FRMécanismes moléculaires dans les démences neurodégénératives

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinitis pigmentosa (RP) is one of the most common forms of inherited retinal degeneration with 1/4,000 people being affected. The vision alteration primarily begins with rod photoreceptor degeneration, then the degenerative process continues with cone photoreceptor death. Variants in 71 genes have been linked to RP. One of these genes,

Indexed as

conesPDE6Aphotoreceptorsretinitis pigmentosarodszebrafish

Identifiers

PMID34095146
PMCPMC8173125
OpenAlexW3163869406

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.