Evidence map›Paper›PMID 34098176›Full record

ArticleJournal of sport and health science2022

Neuromuscular, biomechanical, and energetic adjustments following repeated bouts of downhill running.

Arash Khassetarash, Gianluca Vernillo, Renata L Krüger, W Brent Edwards, Guillaume Y Millet

Open access · diamondAbstract read
In one paragraph

Article in Journal of sport and health science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Arash KhassetarashHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary T2N 1N4, Canada.
Gianluca VernilloHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary T2N 1N4, Canada; Department of Biomedical Sciences for Health, University of Milan, Milan 20133, Italy.
Renata L KrügerHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary T2N 1N4, Canada.
W Brent EdwardsHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary T2N 1N4, Canada.
Guillaume Y MilletHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary T2N 1N4, Canada; Inter-university Laboratory of Human Movement Biology, UJM-Saint-Etienne, Université de Lyon, Saint-Etienne 42023, France; Institut Universitaire de France (IUF), Paris 75231, France. Electronic address: guillaume.millet@univ-st-etienne.fr.
University of Calgary · CAInstitut Universitaire de France · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study used downhill running as a model to investigate the repeated bout effect (RBE) on neuromuscular performance, running biomechanics, and metabolic cost of running.

methodsTen healthy recreational male runners performed two 30-min bouts of downhill running (DR1 and DR2) at a -20% slope and 2.8 m/s 3 weeks apart. Neuromuscular fatigue, level running biomechanics during slow and fast running, and running economy parameters were recorded immediately before and after the downhill bouts, and at 24 h, 48 h, 72 h, 96 h, and 168 h thereafter (i.e., follow-up days).

resultsAn RBE was confirmed by attenuated muscle soreness and serum creatine kinase rise after DR2 compared to DR1. An RBE was also observed in maximum voluntary contraction (MVC) force loss and voluntary activation where DR2 resulted in attenuated MVC force loss and voluntary activation immediately after the run and during follow-up days. The downhill running protocol significantly influenced level running biomechanics; an RBE was observed in which center of mass excursion and, therefore, lower-extremity compliance were greater during follow-up days after DR1 compared to DR2. The observed changes in level running biomechanics did not influence the energy cost of running.

conclusionThis study demonstrated evidence of adaptation in neural drive as well as biomechanical changes with the RBE after DR. The higher neural drive resulted in attenuated MVC force loss after the second bout. It can be concluded that the RBE after downhill running manifests as changes to global and central fatigue parameters and running biomechanics without substantially altering the energy cost of running.

Indexed as

Muscle, SkeletalMyalgiaAdaptation, PhysiologicalBiomechanical PhenomenaHumansLower ExtremityMaleCost of runningEccentric exerciseFatigueMuscle damage

Identifiers

PMID34098176
PMCPMC9189713
OpenAlexW3166023445

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.