Evidence map›Paper›PMID 34099450›Full record

ArticleBMJ case reports2021

Nosocomial SARS-CoV-2 transmission in a neonatal unit in Botswana: chronic overcrowding meets a novel pathogen.

Britt Nakstad, Thato Kaang, Alemayehu Mekonnen Gezmu, Jonathan Strysko

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Britt NakstadDepartment of Paediatric and Adolescent Health, University of Botswana, Gaborone, Botswana britt.nakstad@medisin.uio.no.ORCID http://orcid.org/0000-0002-6843-8100
Thato KaangDepartment of Paediatric and Adolescent Health, University of Botswana, Gaborone, Botswana.
Alemayehu Mekonnen GezmuDepartment of Paediatric and Adolescent Health, University of Botswana, Gaborone, Botswana.
Jonathan StryskoDepartment of Paediatric and Adolescent Health, University of Botswana, Gaborone, Botswana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a cluster of six SARS-CoV-2 infections occurring in a crowded neonatal unit in Botswana, including presumed transmission among mothers, postnatal mother-to-neonate transmission and three neonate-to-healthcare worker transmissions. The affected neonate, born at 25 weeks' gestation weighing 785 g, had a positive SARS-CoV-2 test at 3 weeks of age which coincided with new onset of hypoxaemia and worsening respiratory distress. Because no isolation facility could accommodate both patient and mother, they were separated for 10 days, during which time the patient was switched from breastmilk to formula. Her subsequent clinical course was marked by several weeks of supplemental oxygen, sepsis-like presentations requiring additional antibiotics and bronchopulmonary dysplasia. Despite these complications, adequate growth was achieved likely due to early initiation of nutrition. This nosocomial cluster highlights the vulnerabilities of neonates, caregivers and healthcare workers in an overcrowded environment, and underscores the importance of uninterrupted bonding and breast feeding, even during a pandemic.

Indexed as

COVID-19Cross InfectionPregnancy Complications, InfectiousBotswanaFemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalPregnancySARS-CoV-2COVID-19infection control in hospitalinfectious diseasesneonatal intensive careparenteral / enteral feeding

Identifiers

PMID34099450
PMCPMC8186748

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.