Evidence map›Paper›PMID 34103117›Full record

ArticlePublic health nutrition2021

Food insecurity partially mediates the association between drug use and depressive symptoms among men who have sex with men in Los Angeles, California.

David A Wiss, Marjan Javanbakht, Michael J Li, Michael Prelip, Robert Bolan, Steve Shoptaw, Pamina M Gorbach

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Public health nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

David A WissDepartment of Community Health Sciences, Fielding School of Public Health, University of California, 650 Young Drive South, Los Angeles, CA90095, USA.
Marjan JavanbakhtDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA.
Michael J LiDepartment of Family Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Michael PrelipDepartment of Community Health Sciences, Fielding School of Public Health, University of California, 650 Young Drive South, Los Angeles, CA90095, USA.
Robert BolanLos Angeles LGBT Center, Los Angeles, CA, USA.
Steve ShoptawDepartment of Family Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Pamina M GorbachDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA.
University of California, Los Angeles · USUniversity of Southern California · US

Funding

MSM and Substances Cohort at UCLA Linking Infections Noting Effects (MASCULINE) U01DA036267 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GORBACH, PAMINA MAE, SHOPTAW, STEVEN J · 2013 to 2024
$20.5M
Postdoctoral Training in Global AIDS Prevention ResearchT32MH080634 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JESSE LAWTON CLARK, Pamina Mae Gorbach · 2007 to 2026
$6.4M
Trajectories of socially regulated gene expression, methamphetamine use, and viral load among HIV-positive men who have sex with men (MSM) receiving contingency managementK01DA051329 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LI, MICHAEL JONATHAN · 2021 to 2025
$947k
NIDA NIH HHS K01 DA051329NIDA NIH HHS U01 DA036267NIMH NIH HHS T32 MH080634
6 · The paper itself

Abstract

objectiveTo understand the relationship between drug use, food insecurity (FI) and mental health among men who have sex with men (MSM).

designCohort study (2014-2019) with at least one follow-up.

settingVisits at 6-month intervals included self-assessment for FI and depressive symptoms. Urine testing results confirmed drug use. Factors associated with FI were assessed using multiple logistic regression with random effects for repeated measures. General structural equation modelling tested whether FI mediates the relationship between drug use and depressive symptoms.

participantsData were from HIV-positive and high-risk HIV-negative MSM in Los Angeles, CA (n 431; 1192 visits).

resultsAt baseline, FI was reported by 50·8 % of participants, depressive symptoms in 36·7 % and 52·7 % of urine screening tests were positive for drugs (i.e. marijuana, opioids, methamphetamine, cocaine and ecstasy). A positive drug test was associated with a 96 % increase in the odds of being food insecure (95 % CI 1·26, 3·07). Compared to those with high food security, individuals with very low food security have a nearly sevenfold increase in the odds of reporting depressive symptoms (95 % CI 3·71, 11·92). Findings showed 14·9 % of the association between drug use (exposure) and depressive symptoms (outcome) can be explained by FI (mediator).

conclusionThe prevalence of FI among this cohort of HIV-positive and high-risk HIV-negative MSM was high; the association between drug use and depressive symptoms was partially mediated by FI. Findings suggest that enhancing access to food and nutrition may improve mood in the context of drug use, especially among MSM at risk for HIV transmission.

Indexed as

HIV InfectionsPharmaceutical PreparationsSexual and Gender MinoritiesCohort StudiesDepressionFood InsecurityFood SupplyHomosexuality, MaleHumansLos AngelesMalePharmaceutical PreparationsDepressive symptomsDrug useFood insecurityHIV/AIDSMen who have sex with men

Identifiers

PMID34103117
PMCPMC8387349
OpenAlexW3166930667

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.