Evidence map›Paper›PMID 34106365›Full record

ReviewCardiovascular drugs and therapy2022

Therapeutic Properties of Highly Selective β-blockers With or Without Additional Vasodilator Properties: Focus on Bisoprolol and Nebivolol in Patients With Cardiovascular Disease.

Waleed AlHabeeb, Sanaa Mrabeti, Ahmed Adel Ibrahim Abdelsalam

Open access · hybridAbstract readReview
In one paragraph

Review in Cardiovascular drugs and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Efficacy and Safety of the Extemporaneous Combination Nebivolol/Amlodipine in Patients with Hypertension Uncontrolled on Monotherapy: The BOTTICELLI Study.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
  2. Article
  3. Review
  4. Appraisal of β-Blocker Use in Patients with Cardiovascular Disease and Chronic Obstructive Pulmonary Disease.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Comparison between the ECG Outcomes of Metoprolol and Bisoprolol.Cardiovascular & hematological agents in medicinal chemistry · 2024
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Waleed AlHabeebCardiac Sciences Department, King Saud University, Riyadh, 12372, Saudi Arabia. alhabeebw@yahoo.com.
Sanaa MrabetiGeneral Medicine and Endocrinology, Medical Affairs EMEA, Merck Serono Middle East FZ-LLC, Dubai, United Arab Emirates.
Ahmed Adel Ibrahim AbdelsalamCardiometabolic Care, GCC Medical Affairs, Merck Serono Middle East FZ-LLC, Riyadh, Saudi Arabia.
King Saud University · SAMerck Serono (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisoprolol and nebivolol are highly selective β

Indexed as

Cardiovascular DiseasesHeart FailureHypertensionMyocardial IschemiaAdrenergic beta-AntagonistsBenzopyransBisoprololEthanolaminesHumansNebivololStroke VolumeVasodilator AgentsVentricular Function, LeftAdrenergic beta-AntagonistsBenzopyransBisoprololEthanolaminesNebivololVasodilator AgentsBeta blockadeBisoprololNebivolol

Identifiers

PMID34106365
PMCPMC9519665
OpenAlexW3170462963

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.