SynthesisDeutsches Arzteblatt international2021
The Effect of the Lockdown on Patients With Myocardial Infarction During the COVID-19 Pandemic–A Systematic Review and Meta-Analysis.
Synthesis in Deutsches Arzteblatt international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The collateral damage of COVID-19 to cardiovascular services: a meta-analysis.European heart journal · 2022Pooled it
- Comparison of the Characteristics, Management, and Outcomes of STEMI Patients Presenting With vs. Those of Patients Presenting Without COVID-19 Infection: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- A machine learning model for early risk stratification of 28-day mortality after myocardial infarction.European heart journal. Digital health · 2026Article
- Colchicine in Coronary Artery Disease-Too Much of a Good Thing?Journal of cardiovascular development and disease · 2026Review
- Epidemiological 11-Year Dynamics Study of Acute Myocardial Infarction: A Cohort Study in a Country with a Transitional Healthcare System.Global heart · 2026Observational
- Sedentary Behavior, Physical Inactivity, and the Prevalence of Hypertension, Diabetes, and Obesity During COVID-19 in Brazil.International journal of environmental research and public health · 2025Article
- Enhanced crisis resilience of general practitioner-centred care: a retrospective cohort study of patients with coronary artery disease during the COVID-19 pandemic in Germany.BMC primary care · 2025Article
- Implications and limitations of the CLEAR-SYNERGY trial for the use of low-dose colchicine in cardiovascular disease.Nature cardiovascular research · 2025Article
- Impact of the COVID-19 pandemic on patients with coronary artery disease requiring cardiac surgery at a German university hospital.Journal of cardiothoracic surgery · 2025Article
- Epidemiology and SARIMA model of deaths in a tertiary comprehensive hospital in Hangzhou from 2015 to 2022.BMC public health · 2024Article
- Article
- Post-COVID-19 pandemic organ donation activities in Germany: a multicenter retrospective analysis.Frontiers in public health · 2024Article
- Primary Diagnoses of Squamous Cell Carcinoma of the Head and Neck During the COVID-19 Pandemic.Deutsches Arzteblatt international · 2023Article
- The Impact of COVID-19 National Lockdown on Myocardial Infarction (MI) Hospitalizations in Northern Jordan.Vascular health and risk management · 2023Article
- Cerebro-/Cardiovascular Collateral Damage During the COVID-19 Pandemic: Fact or Fiction?Journal of clinical neurology (Seoul, Korea) · 2023Review
- Dental Emergencies in an Italian Pediatric Hospital during the COVID-19 Pandemic.Healthcare (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe phenomenon of declining numbers of patients presenting with myocardial infarction was reported from the beginning of the COVID-19 pandemic onward. It was thought that measures introduced to stem the pandemic, such as the lockdown, contributed to this development. However, the data on hospital admissions, delay times, and mortality are not consistent.
methodsOur systematic literature review and meta-analysis embraced studies reporting the number of hospital admissions of patients with ST-segment elevation myocardial infarction (STEMI) and/or non-ST-segment elevation myocardial infarction (NSTEMI) during lockdown episodes. We also collected data on patient- and system-related delay times and on mortality.
resultsData from 27 studies on a total of 81 163 patients were included in our meta-analysis. We found that the number of hospital admissions of patients with myocardial infarction was significantly lower during the lockdown than before the pandemic (incidence rate ratio [IRR] = 0.516 [0.403; 0.660], I2 = 98%). This was true both for patients with STEMI (IRR = 0.620 [0.514; 0.746], I2 = 96%) and for patients with NSTEMI (IRR = 0.454 [0.354; 0.584], I2 = 96%). However, we found no significant difference in the time from hospital admission to cardiac catheterization, or in mortality, in relation to the time from symptom onset to first medical contact.
conclusionIn this study, we have shown that the lockdown due to COVID-19 was associated with a marked decline in the number of hospital admissions of patients with myocardial infarction. As no significant effect on delay times or mortality was observed, it seems that timely medical care continued to be delivered.
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