Evidence map›Paper›PMID 34117399›Full record

ReviewEye (London, England)2021

Current and novel multi-imaging modalities to assess retinal oxygenation and blood flow.

Michael J Marino, Peter L Gehlbach, Abhishek Rege, Kim Jiramongkolchai

Abstract readReview
In one paragraph

Review in Eye (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Retinal Hypoxia: Relation to Blood Flow and Oxygen Metabolic Biomarkers.Investigative ophthalmology & visual science · 2026
    Article
  2. Article
  3. Retinal oximetry: new insights into ocular and systemic diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Carbonic anhydrase, its inhibitors and vascular function.Frontiers in molecular biosciences · 2024
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael J Marino *Department of Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.
Peter L Gehlbach *Retina Division, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Abhishek Rege *Vasoptic Medical, Inc., Baltimore, MD, USA.
Kim Jiramongkolchai *Mid-Atlantic Kaiser Permanente, McLean, VA, USA. jiramong@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinal ischemia characterizes the underlying pathology in a multitude of retinal diseases that can ultimately lead to vision loss. A variety of novel imaging modalities have been developed to characterize retinal ischemia by measuring retinal oxygenation and blood flow in-vivo. These technologies offer valuable insight into the earliest pathophysiologic changes within the retina and provide physicians and researchers with new diagnostic and monitoring capabilities. Future retinal imaging technologies with the capability to provide affordable, noninvasive, and comprehensive data on oxygen saturation, vasculature, and blood flow mechanics are needed. This review will highlight current and future trends in multimodal imaging to assess retinal blood flow and oxygenation.

Indexed as

OxygenRetinal DiseasesDiagnostic ImagingHumansRegional Blood FlowRetinaOxygen

Identifiers

PMID34117399
PMCPMC8526664

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.