Evidence map›Paper›PMID 34119296›Full record

ReviewJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia2021

Isolated abducens nerve palsy in a patient with asymptomatic SARS-CoV-2 infection.

Aishwarya Anilkumar, Elizabeth Tan, Jonathan Cleaver, Hamish D Morrison

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Isolated Sixth Nerve Palsy and COVID-19: A Recurrent Case in a 7-Month-Old Child and Analysis of Reported Cases.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Aishwarya AnilkumarDepartment of Neurology, North Bristol NHS Trust, Bristol BS10 5NB, UK.
Elizabeth TanDepartment of Neurology, North Bristol NHS Trust, Bristol BS10 5NB, UK.
Jonathan CleaverDepartment of Neurology, North Bristol NHS Trust, Bristol BS10 5NB, UK.
Hamish D MorrisonDepartment of Neurology, North Bristol NHS Trust, Bristol BS10 5NB, UK; Population Health Sciences, University of Bristol, Bristol BS8 2PL, UK. Electronic address: hamish.morrison@nhs.net.
North Bristol NHS Trust · GBUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neuro-ophthalmological complications of SARS-CoV-2 infection are emerging but the spectrum of presentations and pathophysiological mechanism underpinning the association remains to be fully determined. We describe the case of a 44-year-old female who presented with a 12-hour history of diplopia preceded by a mild headache and found to have an isolated right abducens nerve palsy. Initial vital signs were normal but she developed a fever and nasopharyngeal swab confirmed SARS-CoV-2 infection by RT-PCR. All other investigations returned normal including blood tests, chest X-ray, MRI brain and cerebrospinal fluid analysis. She remained systemically well, and there was complete resolution of the abducens palsy and diplopia at two week follow up. In the absence of an alternative underlying cause or risk factors identified, the aetiology was presumed to be microvascular and potentially related to the viral infection. We add to the evolving literature of neuro-ophthalmological associations of SARS-CoV-2, discuss possible causal mechanisms and suggest considering asymptomatic SARS-CoV-2 infection in cases of isolated abducens palsy without clear risk factors.

Indexed as

Asymptomatic DiseasesAbducens Nerve DiseasesAdultCOVID-19DiplopiaFemaleHumansMagnetic Resonance ImagingSARS-CoV-2Abducens nerve palsyNeuro-ophthalmological complicationsSARS-CoV-2 infection

Identifiers

PMID34119296
PMCPMC8055164
OpenAlexW3155096170

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.