Evidence map›Paper›PMID 34120091›Full record

ArticleNeurobiology of aging2021

Red cell distribution width, anemia and their associations with white matter integrity among middle-aged urban adults.

May A Beydoun, Danielle Shaked, Sharmin Hossain, Jordan Weiss, Hind A Beydoun, Ana I Maldonado, Leslie I Katzel, Christos Davatzikos, Rao P Gullapalli, Stephen L Seliger and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurobiology of aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

May A BeydounLaboratory of Epidemiology and Population Sciences, NIA/NIH/IRP, Baltimore, MD, USA. Electronic address: baydounm@mail.nih.gov.
Danielle ShakedDepartment of Psychology, VA Boston Healthcare System, Boston, MA, USA.
Sharmin HossainLaboratory of Epidemiology and Population Sciences, NIA/NIH/IRP, Baltimore, MD, USA.
Jordan WeissDepartment of Demography, University of California, Berkeley, Berkeley, CA, USA.
Hind A BeydounDepartment of Research Programs, Fort Belvoir Community Hospital, Fort Belvoir, VA, USA.
Ana I MaldonadoLaboratory of Epidemiology and Population Sciences, NIA/NIH/IRP, Baltimore, MD, USA; Department of Psychology, University of Maryland Baltimore County, Catonsville, MD, USA.
Leslie I KatzelGeriatric Research Education and Clinical Center, Baltimore VA Medical Center, Baltimore, MD, USA; Division of Gerontology & Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Christos DavatzikosArtificial Intelligence in Biomedical Imaging Lab, Center for Biomedical Image Computing and Analytics (CBICA), Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
Rao P GullapalliDepartment of Diagnostic Radiology, University of Maryland School of Medicine, Baltimore, MD, USA.
Stephen L SeligerDivision of Nephrology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Guray ErusArtificial Intelligence in Biomedical Imaging Lab, Center for Biomedical Image Computing and Analytics (CBICA), Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
Michele K EvansLaboratory of Epidemiology and Population Sciences, NIA/NIH/IRP, Baltimore, MD, USA.
Alan B ZondermanLaboratory of Epidemiology and Population Sciences, NIA/NIH/IRP, Baltimore, MD, USA.
Shari R WaldsteinDepartment of Psychology, University of Maryland Baltimore County, Catonsville, MD, USA; Geriatric Research Education and Clinical Center, Baltimore VA Medical Center, Baltimore, MD, USA; Division of Gerontology & Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
University of Maryland, Baltimore · USIntel (United States) · USAlexander T. Augusta Military Medical Center · USNational Institute on Aging · USUniversity of California, Berkeley · USUniversity of Maryland, Baltimore County · USVA Boston Healthcare System · US

Funding

Healthy Aging In Neighborhoods of Diversity Across the Life Span (HANDLS)ZIAAG000513 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2009 to 2025
$70.9M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
Healthy Aging Neighborhoods of Diversity Across LifespanZ01AG000513 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2001 to 2008
$6.8M
Machine Learning and Large-scale Imaging analytics for dimensional representations of brain trajectories in aging and preclinical Alzheimer's Disease: The brain aging chart and the iSTAGING consortiumRF1AG054409 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2017 to 2023
$6.3M
HANDLS Scan Substudy: Race, Socioeconomic status, and the BrainR01AG034161 · NIA · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI WALDSTEIN, SHARI · 2009 to 2013
$2.8M
Intramural NIH HHS Z01 AG000513Intramural NIH HHS Z99 AG999999NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG034161NIA NIH HHS RF1 AG054409
6 · The paper itself

Abstract

Anemia (blood hemoglobin [Hb] <13 g/dL among males; <12 g/dL among females) and elevated red cell distribution width (RDW) are potential risk factors for reduced brain white matter integrity (WMI), reflected by lower fractional anisotropy or increased mean diffusivity. Cross-sectional data with exposure-outcome lag time was used, whereby hematological exposures (RDW and Hb) and covariates were compiled from the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study with available visit 1 (v

Indexed as

AnemiaErythrocyte IndicesUrban PopulationAdultAgedAgingAnisotropyDatabases as TopicDiffusion Tensor ImagingFemaleHumansMaleMiddle AgedRisk FactorsSex CharacteristicsWhite MatterAgingAnemiaRed cell distribution widthWhite matter integrity

Identifiers

PMID34120091
PMCPMC8338752
OpenAlexW3164096065

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.