Evidence map›Paper›PMID 34122608›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Gastrointestinal Motility and Gut Hormone Secretion in response to Shenhuang Plaster in a Postoperative Ileus Rat Model.

Yanan Shi, Yingsong Zheng, Jingming Xu, Bin Ding, Qiyang Shou, Guiping Chen, Ting Liu, Qiuhua Sun, Xiaohong Xu

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yanan ShiSchool of Nursing, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0002-1282-4627
Yingsong ZhengThe First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0002-2984-7884
Jingming XuThe First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0002-8703-0477
Bin DingCollege of Life Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0002-4009-5820
Qiyang ShouSchool of Second Clinical Medical, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0003-1615-5309
Guiping ChenThe First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310018, China.ORCID https://orcid.org/0000-0002-0963-5681
Ting LiuSchool of Nursing, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0003-0593-5529
Qiuhua SunSchool of Nursing, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0001-7916-3408
Xiaohong XuThe First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310018, China.ORCID https://orcid.org/0000-0001-7683-4472
Zhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative ileus (POI), a gastrointestinal function disorder, is a complication that arises from surgery. Shenhuang plaster (SHP) application to the Shenque acupoint (CV8) to promote the recovery of gastrointestinal function has achieved definite curative effects in clinical settings; however, the underlying pharmacological mechanism remains unknown. In this study, we evaluated the effects of SHP using a Sprague Dawley rat POI model. Then, gastrointestinal transit in different rat groups was evaluated by the movement of fluorescein-labelled dextran. Ghrelin, obestatin, motilin (MTL), and vasoactive intestinal peptide (VIP) plasma concentrations were measured via a radioimmunoassay. The expression of the ghrelin and obestatin receptors (GHS-R1

Identifiers

PMID34122608
PMCPMC8189788
OpenAlexW3168020614

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.