Evidence map›Paper›PMID 34128346›Full record

GuidelineUnited European gastroenterology journal2021

European guideline on indications, performance and clinical impact of

Jutta Keller, Heinz F Hammer, Paul R Afolabi, Marc Benninga, Osvaldo Borrelli, Enrique Dominguez-Munoz, Dan Dumitrascu, Oliver Goetze, Stephan L Haas, Bruno Hauser and 7 more

Open access · bronzeAbstract readPractice GuidelineReview
In one paragraph

Guideline in United European gastroenterology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Guideline
  4. Guideline
  5. Article
  6. Expanding theACS central science · 2026
    Article
  7. Pancreatic exocrine insufficiency.EClinicalMedicine · 2026
    Review
  8. Review
  9. Article
  10. Review
  11. Association of TyG and TyG/HDL withFrontiers in medicine · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. World journal of gastroenterology · 2025
    Article
  17. ACS sensors · 2025
    Article
  18. Review
  19. Quality of clinical guidelines: It matters as it impacts patient care.United European gastroenterology journal · 2024
    Article
  20. Cardio-Hepatic Interaction in Cardiac Amyloidosis.Journal of clinical medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 13 institutions in 11 countries.

Jutta KellerDepartment of Internal Medicine, Israelitic Hospital, Academic Hospital University of Hamburg, Hamburg, Germany.ORCID 0000-0002-5884-1115
Heinz F HammerDepartment of Internal Medicine, Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria.ORCID 0000-0001-8683-4951
Paul R AfolabiNIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.
Marc BenningaDepartment of Pediatric Gastroenterology, Hepatology and Nutrition, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Osvaldo BorrelliUCL Great Ormond Street Institute of Child Health and Department of Gastroenterology, Neurogastroenterology and Motility, Great Ormond Street Hospital, London, UK.
Enrique Dominguez-MunozDepartment of Gastroenterology and Hepatology, University Hospital of Santiago de Compostela, Santiago, Spain.
Dan DumitrascuClinica Medicala 2, Cluj-Napoca, Romania.
Oliver GoetzeDepartment of Medicine II, Division of Hepatology, University Hospital Würzburg, Würzburg, Germany.
Stephan L HaasDepartment of Upper GI Diseases, Karolinska University Hospital, Stockholm, Sweden.
Bruno HauserDepartment of Paediatric Gastroenterology, Hepatology and Nutrition, KidZ Health Castle UZ Brussels, Brussels, Belgium.
Daniel PohlDivision of Gastroenterology and Hepatology, University Hospital Zürich, Zürich, Switzerland.
Silvia SalvatorePediatric Department, Hospital "F. Del Ponte", University of Insubria, Varese, Italy.
Marc SonyiDepartment of Internal Medicine, Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria.
Nikhil ThaparUCL Great Ormond Street Institute of Child Health and Department of Gastroenterology, Neurogastroenterology and Motility, Great Ormond Street Hospital, London, UK.
Kristin VerbekeTranslational Research Center for Gastrointestinal Disorders, KU Leuven, Leuven, Belgium.
Mark R FoxDivision of Gastroenterology and Hepatology, University Hospital Zürich, Zürich, Switzerland.ORCID 0000-0003-4394-5584
European 13C-breath test group
Great Ormond Street Hospital · GBMedical University of Graz · ATUniversity Hospital of Zurich · CHBelgian Health Care Knowledge Centre (KCE) · BEEmma Kinderziekenhuis · NLKarolinska University Hospital · SEKU Leuven · BESpitalul Clinic de Recuperare · ROUniversidade de Santiago de Compostela · ESUniversität Hamburg · DEUniversitätsklinikum Würzburg · DEUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Insubria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction

methodsThis consensus-based clinical practice guideline defines the clinical indications, performance, and interpretation of

resultsThe guideline gives an overview over general methodology of

conclusionThis clinical practice guideline should improve pan-European harmonization of diagnostic approaches to symptoms and disorders, which are very common in specialist and primary care gastroenterology practice, both in adult and pediatric patients. In addition, this guideline identifies areas of future clinical research involving the use of

Indexed as

ConsensusGastric EmptyingHelicobacter pyloriAdultBreath TestsCarbon IsotopesChildDelphi TechniqueEuropeHelicobacter InfectionsHumansLiverLiver Function TestsPancreas, ExocrinePancreatic Function TestsUreaCarbon IsotopesUreabreathtestdiagnosisgastroenterologygastroparesishelicobacter pyloriliver cirrhosismotilitypancreatic exocrine insufficiencypancreatitis

Identifiers

PMID34128346
PMCPMC8259225
OpenAlexW3167421446

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.