Evidence map›Paper›PMID 34128443›Full record

ArticleChronobiology international2021

Circadian characteristics of the rest-activity rhythm, executive function, and glucose fluctuations in young adults with type 1 diabetes.

Stephanie Griggs, Kingman P Strohl, Margaret Grey, Eric Barbato, Seunghee Margevicius, Ronald L Hickman

Open access · greenAbstract read
In one paragraph

Article in Chronobiology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

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  10. Cognitive benefits of sleep: a narrative review to explore the relevance of glucose regulation.Sleep advances : a journal of the Sleep Research Society · 2025
    Review
  11. Review
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  13. Age Is Associated With Dampened Circadian Patterns of Rest and Activity: The Study of Muscle, Mobility, and Aging (SOMMA).The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Stephanie GriggsFrances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, USA.ORCID 0000-0001-9901-3853
Kingman P StrohlDepartment of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.ORCID 0000-0001-7740-9013
Margaret GreySchool of Nursing and School of Medicine, Yale University, West Haven, Connecticut, USA.ORCID 0000-0003-2473-8088
Eric BarbatoDepartment of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.ORCID 0000-0001-8132-0679
Seunghee MargeviciusDepartment of Population and Quantitative Health Sciences, School of Medicine, Cleveland, Ohio, USA.ORCID 0000-0001-5663-8319
Ronald L HickmanFrances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, USA.ORCID 0000-0002-3720-2955
Case Western Reserve University · USQuantitative BioSciences · USYale University · US

Funding

Research Training: Self and Family ManagementT32NR008346 · NINR · YALE UNIVERSITY · PI GREY, MARGARET · 2003 to 2018
$4.7M
Sleep, Glycemia, and Self-Management in Young Adults with Type 1 Diabetes MellitusR00NR018886 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI GRIGGS, STEPHANIE ALISHA · 2021 to 2023
$729k
Sleep, Glycemia, and Self-Management in Young Adults with Type 1 Diabetes MellitusK99NR018886 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI GRIGGS, STEPHANIE ALISHA · 2020 to 2020
$93k
NINR NIH HHS K99 NR018886NINR NIH HHS R00 NR018886NINR NIH HHS T32 NR008346
6 · The paper itself

Abstract

Circadian alignment is an important element in individual health, and one behavioral marker, rest-activity rhythm, could influence self-management in young adults with type 1 diabetes (T1D). Little is known about the rest-activity rhythms, executive function, and glycemia among young adults with type 1 diabetes (T1D). The purpose of this study was to evaluate parametric and nonparametric circadian characteristics of the rest-activity rhythm and the associations between these variables, sleep-wake behavior, executive function, and glycemia among young adults with T1D. Young adults with T1D, recruited from diabetes clinics, wore wrist actigraphs and a continuous glucose monitor (CGM) concurrently for 6-14 days. Participants completed a 3-minute Trail Making Test on paper and electronic questionnaires - 8-item PROMIS v1.0 Emotional Distress Scale, 17-item Diabetes Distress Scale, including twice-daily Pittsburgh sleep diaries. Cosinor and nonparametric analyses were used to compute the rest-activity rhythm parameters, and linear regression modeling procedures were performed to determine the associations among the study variables. The sample included 46 young adults (mean age 22.3 ± 3.2; 32.6% male; 84.8% non-Hispanic White, HbA1c mean 7.2 ± 1.1%, BMI mean 27.0 ± 4.4 kg/m

Indexed as

Diabetes Mellitus, Type 1ActigraphyAdultCircadian RhythmExecutive FunctionFemaleGlucoseHumansMaleSleepYoung AdultGlucoseactigraphyCircadian rest-activity rhythmcosinor analysisdiabetes self-managementsleeptype 1 diabetesyoung adult

Identifiers

PMID34128443
PMCPMC8403141
OpenAlexW3172920776

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.