Evidence map›Paper›PMID 34128772›Full record

SynthesisPathogens and global health

Hydroxychloroquine and mortality in COVID-19 patients: a systematic review and a meta-analysis of observational studies and randomized controlled trials.

Augusto Di Castelnuovo, Simona Costanzo, Antonio Cassone, Roberto Cauda, Giovanni De Gaetano, Licia Iacoviello

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Pathogens and global health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Comprehensive evaluation of six interventions for hospitalized patients with COVID-19: A propensity score matching study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  7. Article
  8. Review
  9. Review
  10. Medicina (Kaunas, Lithuania) · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Augusto Di CastelnuovoMediterranea Cardiocentro, Naples, Italy.ORCID 0000-0001-9767-7998
Simona CostanzoDepartment of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli (IS), Italy.ORCID 0000-0003-4569-1186
Antonio CassonePolo Della Genomica, Genetica E Biologia, Università Di Siena, Siena, Italy.ORCID 0000-0002-0434-0761
Roberto CaudaFondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica S. Cuore Roma, Italy.ORCID 0000-0002-1498-4229
Giovanni De GaetanoDepartment of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli (IS), Italy.ORCID 0000-0002-7823-1402
Licia IacovielloDepartment of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli (IS), Italy.ORCID 0000-0003-0514-5885

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19 Drug TreatmentHydroxychloroquineAntiviral AgentsChloroquineHumansRandomized Controlled Trials as TopicSARS-CoV-2Treatment OutcomeAntiviral AgentsChloroquineHydroxychloroquineCOVID-19hydroxychloroquinemortalitySARS-COV-2

Identifiers

PMID34128772
PMCPMC8220439

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.