Evidence map›Paper›PMID 34145392›Full record

ArticleThe ISME journal2021

Methanogenic archaea use a bacteria-like methyltransferase system to demethoxylate aromatic compounds.

Julia M Kurth, Masaru K Nobu, Hideyuki Tamaki, Nadieh de Jonge, Stefanie Berger, Mike S M Jetten, Kyosuke Yamamoto, Daisuke Mayumi, Susumu Sakata, Liping Bai and 5 more

Open access · hybridAbstract read
In one paragraph

Article in The ISME journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 87 citations in OpenAlex.

  1. Gut microbes · 2026
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  8. An integrated culturomic and genomic database and analysis platform for methanogenic archaea.Database : the journal of biological databases and curation · 2026
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  14. Methionine synthesis and glycine betaine demethylation are intricately intertwined in cosmopolitan marine bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  18. Bacterial estrogenesis without oxygen: Wood-Ljungdahl pathway likely contributed to the emergence of estrogens in the biosphere.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 5 countries.

Julia M Kurth *Department of Microbiology, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands.
Masaru K Nobu *Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan. m.nobu@aist.go.jp.ORCID http://orcid.org/0000-0002-0046-9306
Hideyuki TamakiBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.
Nadieh de JongeDepartment of Chemistry and Bioscience, Aalborg University, Aalborg East, Denmark.
Stefanie BergerDepartment of Microbiology, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands.
Mike S M JettenDepartment of Microbiology, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands.
Kyosuke YamamotoBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Sapporo, Japan.ORCID http://orcid.org/0000-0003-2450-779X
Daisuke MayumiInstitute for Geo-Resources and Environment, Geological Survey of Japan, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.
Susumu SakataInstitute for Geo-Resources and Environment, Geological Survey of Japan, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.
Liping BaiKey Laboratory of Energy Microbiology and Its Application of Ministry of Agriculture, Biogas Institute of Ministry of Agriculture, Chengdu, China.
Lei ChengKey Laboratory of Energy Microbiology and Its Application of Ministry of Agriculture, Biogas Institute of Ministry of Agriculture, Chengdu, China.ORCID http://orcid.org/0000-0003-1178-8190
Jeppe Lund NielsenDepartment of Chemistry and Bioscience, Aalborg University, Aalborg East, Denmark.ORCID http://orcid.org/0000-0002-8747-6938
Yoichi KamagataBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.
Tristan WagnerMicrobial Metabolism research group, Max Planck Institute for Marine Microbiology, Bremen, Germany.
Cornelia U WelteDepartment of Microbiology, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands. c.welte@science.ru.nl.ORCID http://orcid.org/0000-0002-1568-8878
National Institute of Advanced Industrial Science and Technology · JPRadboud University Nijmegen · NLAalborg University · DKBiogas Institute of Ministry of Agriculture · CNGeological Survey of Japan · JPMax Planck Institute for Marine Microbiology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methane-generating archaea drive the final step in anaerobic organic compound mineralization and dictate the carbon flow of Earth's diverse anoxic ecosystems in the absence of inorganic electron acceptors. Although such Archaea were presumed to be restricted to life on simple compounds like hydrogen (H

Indexed as

EuryarchaeotaMethyltransferasesMethaneMethaneMethyltransferases

Identifiers

PMID34145392
PMCPMC8630106
OpenAlexW3167715478

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.