ArticleAmerican journal of translational research2021
The relationship between the carotid atherosclerosis ultrasound parameters and the cardiac and endothelial functions of coronary heart disease patients.
Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Article
- Serum Nitric Oxide, Endothelin-1 Correlates Post-Procedural Major Adverse Cardiovascular Events among Patients with Acute STEMI.Arquivos brasileiros de cardiologia · 2025Article
- Predictive value of percutaneous peripheral arterial compliance T in left ventricular diastolic function with coronary artery disease.Frontiers in cardiovascular medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to discover the relationship between the carotid atherosclerosis ultrasound parameters and the cardiac and endothelial functions of coronary heart disease patients.
methods150 patients with coronary artery disease were divided into a single-branch group (one coronary artery with stenosis > 50%), a double-branch group (two coronary arteries with stenosis > 50%), and a multi-branch group (multiple coronary arteries with stenosis > 50%) based on the severity of each patient's coronary stenosis. Meanwhile, 50 healthy volunteers who were admitted to the hospital for routine health checks were recruited as the control group. This study tested the ultrasound parameters of carotid artery atherosclerosis among all the subjects in each group [common carotid artery sclerosis (β), carotid artery compliance (AC), elastic coefficient (Ep), pulse wave conduction velocity (PWVβ)], including the left ventricular end diastolic inner diameter (LVEDD), left ventricular ejection fraction (LVEF) and endothelial function parameters [endothelin-1 (ET-1), von Willebrand factor (vWF), and nitric oxide (NO)].
resultsThe study found that the β, AC, Ep, PWVβ, LVEDD, LVESD, ET-1, and vWF levels of patients with coronary artery disease were all higher than the corresponding levels in the control group (P < 0.05). The values increased as the number of coronary artery branches with stenosis increased (P < 0.05). The LVEF and NO of the patients with coronary artery disease were lower than they were in the control group (P < 0.05). The LVEF and NO decreased as the coronary artery branches with stenosis increased (P < 0.05). The correlation analysis indicated that the ultrasound parameter of carotid atherosclerosis has a significant positive relation with the LVEDD, LVESD, ET-1, and vWF levels (P < 0.05) and a negative relation with the LVEF and NO levels (P < 0.05).
conclusionThe ultrasound parameter of carotid atherosclerosis, cardiac function, and endothelial function can be used for the early diagnosis of coronary heart disease.
Indexed as
Identifiers
34150149PMC8205754W3174573471What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.