Evidence map›Paper›PMID 34150620›Full record

ArticleFrontiers in oncology2021

Chrysin Induced Cell Apoptosis Through

Lin Chen, Qirong Li, Ziping Jiang, Chengshun Li, Haobo Hu, Tiedong Wang, Yan Gao, Dongxu Wang

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Review
  3. Resveratrol targets mitochondrial USP36-SOD2 to induce autophagy-ferroptosis and inhibit gastric cancer progression.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Competing endogenous RNAs (ceRNAs) and drug resistance to cancer therapy.Cancer drug resistance (Alhambra, Calif.) · 2024
    Review
  11. Review
  12. Review
  13. Article
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  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lin ChenLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Qirong LiLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Ziping JiangDepartment of Hand Surgery, The First Hospital of Jilin University, Changchun, China.
Chengshun LiLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Haobo HuLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Tiedong WangLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Yan GaoLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Dongxu WangLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChrysin is a natural flavone that is present in honey and has exhibited anti-tumor properties. It has been widely studied as a therapeutic agent for the treatment of various types of cancers. The objectives of this present study were to elucidate how chrysin regulates non-coding RNA expression to exert anti-tumor effects in gastric cancer cells.

methodsThrough the use of RNA sequencing, we investigated the differential expression of mRNAs in gastric cancer cells treated with chrysin. Furthermore,

resultsOur results identified

conclusionsThis study suggests that chrysin exhibited anti-tumor effects through a

Indexed as

chrysinCOPB2gastric cancerH19let-7a

Identifiers

PMID34150620
PMCPMC8209501

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.