Evidence map›Paper›PMID 34159813›Full record

SynthesisJournal of pharmacy practice2023

Medicines Related Problems (MRPs) Originating in Primary Care Settings in Older Adults - A Systematic Review.

Rosetta Chinyere Ude-Okeleke, Zoe Aslanpour, Soraya Dhillon, Nkiruka Umaru

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Journal of pharmacy practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rosetta Chinyere Ude-OkelekeSchool of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom.ORCID 0000-0002-4154-8297
Zoe AslanpourSchool of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom.
Soraya DhillonSchool of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom.
Nkiruka UmaruSchool of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom.
University of Hertfordshire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs people age, they become increasingly vulnerable to the untoward effects of medicines due to changes in body systems. These may result in medicines related problems (MRPs) and consequent decline or deterioration in health.

aimTo identify MRPs, indicators of deterioration associated with these MRPs, and preventative interventions from the literature. DESIGN AND

settingSystematic review of primary studies on MRPs originating in Primary Care in older people.

methodsRelevant studies published between 2001 and April 2018 were obtained from Medline (via PubMed), CINAHL, Embase, Psych Info, PASCAL, Scopus, Cochrane Library, Science Direct, and Zetoc. Falls, delirium, pressure ulcer, hospitalization, use of health services and death were agreed indicators of deterioration. The methodological quality of included studies was assessed using the Down and Black tool.

resultsThere were 1858 articles retrieved from the data bases. Out of these, 21 full text articles met inclusion criteria for the review. MRPs identified were medication error, potentially inappropriate medicines, adverse drug reaction and non-adherence. These were associated with indicators of deterioration. Interventions that involved doctors, pharmacists and patients in planning and implementation yielded benefits in halting MRPs.

conclusionThis Systematic review summarizes MRPs and associated indicators of deterioration. Appropriate interventions appeared to be effective against certain MRPs and their consequences. Further studies to explore deterioration presented in this systematic review is imperative.

Indexed as

Drug-Related Side Effects and Adverse ReactionsPhysiciansAgedHumansMedication ErrorsPharmacistsPrimary Health CaregeriatricsMRPsolder personspharmaceutical care issuesprimary health care

Identifiers

PMID34159813
PMCPMC10068399
OpenAlexW3173986673

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.