Evidence mapPaperPMID 34169439Full record

ArticleThe AAPS journal2021

Formoterol PLGA-PEG Nanoparticles Induce Mitochondrial Biogenesis in Renal Proximal Tubules.

Ernest L Vallorz, Karen Blohm-Mangone, Rick G Schnellmann, Heidi M Mansour

Open access · greenAbstract read
In one paragraph

Article in The AAPS journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  5. βBiochemistry research international · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ernest L VallorzDepartment of Pharmacology and Toxicology, The University of Arizona College of Pharmacy, Tucson, Arizona, 85721, USA.
Karen Blohm-MangoneDepartment of Pharmacology and Toxicology, The University of Arizona College of Pharmacy, Tucson, Arizona, 85721, USA.
Rick G SchnellmannDepartment of Pharmacology and Toxicology, The University of Arizona College of Pharmacy, Tucson, Arizona, 85721, USA.
Heidi M MansourDepartment of Pharmacology and Toxicology, The University of Arizona College of Pharmacy, Tucson, Arizona, 85721, USA. mansour@pharmacy.arizona.edu.
University of Arizona · USSouthern Arizona VA Health Care System · US

Funding

VITAMIN AP30CA023074 · UNIVERSITY OF ARIZONA · 1985 to 2025
$23.1M
SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · UNIVERSITY OF ARIZONA · 1994 to 2025
$7.3M
NCI NIH HHS P30 CA023074NIEHS NIH HHS P30 ES006694NIH HHS S10 OD011981
6 · The paper itself

Abstract

Formoterol is a long-acting β

Indexed as

Adrenergic beta-2 Receptor AgonistsAnimalsCells, CulturedDrug LiberationFemaleFormoterol FumarateHumansKidney Tubules, ProximalMaleMiceMitochondriaModels, AnimalNanoparticle Drug Delivery SystemOrganelle BiogenesisPolyethylene GlycolsPolylactic Acid-Polyglycolic Acid CopolymerAdrenergic beta-2 Receptor AgonistsFormoterol FumarateNanoparticle Drug Delivery SystemPolyethylene GlycolsPolylactic Acid-Polyglycolic Acid Copolymercontrolled drug releaseformoterolmitochondrial biogenesisnanoparticles kidneyprimary cell culture

Identifiers

PMID34169439
PMCPMC8734428
OpenAlexW3175300667

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.