ArticleScientific reports2021
Recanalization strategies in childhood stroke in Germany.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Incidence and Prognosis of Pediatric Stroke in Denmark: A Nationwide Population-Based Study.Neurology · 2025Article
- Outcome of Pediatric Large Vessel Occlusion Stroke in Denmark.Stroke (Hoboken, N.J.) · 2024Article
- Pediatric intensive care unit admissions network-rationale, framework and method of operation of a nationwide collaborative pediatric intensive care research network in Germany.Frontiers in pediatrics · 2023Article
- [Arterial ischemic stroke in childhood and adolescence : Time-critical emergency in pediatrics].Der Nervenarzt · 2022Article
- [Stroke alarm-Arterial ischemic stroke as one of the most time-critical emergencies in children and adolescents].Der Nervenarzt · 2022Review
- Administrative data in pediatric critical care research-Potential, challenges, and future directions.Frontiers in pediatrics · 2022Article
- Hyperacute treatment of childhood stroke in Lyme neuroborreliosis: report of two cases and systematic review of the literature.Therapeutic advances in neurological disorders · 2022Article
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood arterial ischemic stroke (CAIS) is a rare event. Diverse etiologies, risk factors, symptoms and stroke mimics hamper obtaining a fast diagnosis and implementing immediate recanalization strategies. Over a period of 3 years (2015-2017), the data of 164 pediatric patients (> 28 days of life-18 years) with a first episode of AIS were submitted to a hospital-based nationwide surveillance system for rare disorders (ESPED). We report a subgroup analysis of patients who have undergone recanalization therapy and compare these data with those of the whole group. Twenty-eight patients (17%) with a median age of 12.2 years (range 3.3-16.9) received recanalization therapy. Hemiparesis, facial weakness and speech disturbance were the main presenting symptoms. The time from onset of symptoms to confirmation of diagnosis was significantly shorter in the intervention group (4.1 h vs. 20.4 h, p ≤ 0.0001). Only in one patient occurred a minor bleed. Cardiac disease as predisposing risk factor was more common in the recanalization group. Recanalization therapies are feasible and increasingly applied in children with AIS. High awareness, timely diagnosis and a large amount of expertise may improve time to treatment and make hyperacute therapy an option for more patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.