Evidence map›Paper›PMID 34174282›Full record

ReviewJournal of neuroscience methods2021

Brain imaging-based machine learning in autism spectrum disorder: methods and applications.

Ming Xu, Vince Calhoun, Rongtao Jiang, Weizheng Yan, Jing Sui

Open access · greenAbstract readReview
In one paragraph

Review in Journal of neuroscience methods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Ming XuBrainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China 100190; School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China 100049.
Vince CalhounTri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, and Emory University, Atlanta, GA, USA 30303.
Rongtao JiangBrainnetome Center and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China 100190.
Weizheng YanTri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, and Emory University, Atlanta, GA, USA 30303.
Jing SuiState Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China 100088. Electronic address: jsui@bnu.edu.cn.
Beijing Normal University · CNChinese Academy of Sciences · CNGeorgia Institute of Technology · USGeorgia State University · USInstitute of Automation · CN

Funding

Transcranial Direct Current Stimulation for Treatment of Auditory Verbal HalluciP20GM103472 · NIGMS · THE MIND RESEARCH NETWORK · PI CALHOUN, VINCE D · 2012 to 2017
$14.3M
Informed Data-Driven Fusion of Behavior, Brain Function, and GenesR01EB005846 · NIBIB · THE MIND RESEARCH NETWORK · PI CALHOUN, VINCE D · 2005 to 2016
$5.5M
Data-driven approaches to identify biomarkers from multimodal imaging big dataR01MH117107 · NIMH · GEORGIA STATE UNIVERSITY · PI CALHOUN, VINCE D · 2019 to 2022
$1.6M
NIBIB NIH HHS R01 EB005846NIGMS NIH HHS P20 GM103472NIMH NIH HHS R01 MH117107
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental condition with early childhood onset and high heterogeneity. As the pathogenesis is still elusive, ASD diagnosis is comprised of a constellation of behavioral symptoms. Non-invasive brain imaging techniques, such as magnetic resonance imaging (MRI), provide a valuable objective measurement of the brain. Many efforts have been devoted to developing imaging-based diagnostic tools for ASD based on machine learning (ML) technologies. In this survey, we review recent advances that utilize machine learning approaches to classify individuals with and without ASD. First, we provide a brief overview of neuroimaging-based ASD classification studies, including the analysis of publications and general classification pipeline. Next, representative studies are highlighted and discussed in detail regarding different imaging modalities, methods and sample sizes. Finally, we highlight several common challenges and provide recommendations on future directions. In summary, identifying discriminative biomarkers for ASD diagnosis is challenging, and further establishing more comprehensive datasets and dissecting the individual and group heterogeneity will be critical to achieve better ADS diagnosis performance. Machine learning methods will continue to be developed and are poised to help advance the field in this regard.

Indexed as

Autism Spectrum DisorderBrainChild, PreschoolHumansMachine LearningMagnetic Resonance ImagingNeuroimagingAutism spectrum disorder (ASD)ClassificationdMRIfMRIMachine learningPredictionsMRI

Identifiers

PMID34174282
PMCPMC9006225
OpenAlexW3175210941

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.